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• W2955994631 abstract "Salpratlactones A (1) and B (2), a pair of abietane cis–trans tautomers from Salvia prattii, were identified as the first naturally occurring agonists of T-type calcium channel (TTCC). Structurally, 1 and 2 were featured by unique 6/5 carbocyclic rings bearing a γ-lactone ring through an exocyclic double bond. Moreover, both compounds and their mixture at 10 μM potently and equally increased Cav3.1 TTCC peak currents, and 1 had an EC50 value of 12.48 μM." @default.
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• W2955994631 date "2019-07-03" @default.
• W2955994631 modified "2023-10-03" @default.
• W2955994631 title "Salpratlactones A and B: A Pair of <i>cis</i>–<i>trans</i> Tautomeric Abietanes as Ca_v3.1 T-Type Calcium Channel Agonists from <i>Salvia prattii</i>" @default.
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• W2955994631 doi "https://doi.org/10.1021/acs.orglett.9b01527" @default.
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