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- W2955997137 abstract "Abstract Analysis of transcriptomic data derived from blood samples is complicated by the complex mixture of cell types such samples contain. Transcriptomic signatures derived from such samples are often driven by a particular cell lineage within the mixture. Identifying this most contributing lineage can help to provide a biological interpretation of the signature. We created a web application CellTypeScore which quantifies and visually represents the expression level of signature genes in common blood cell types. This is done by constructing an interactive stacked bar plot with the bars representing expression of genes across blood cell types. Summed scores serve as a measure of how highly the combined signature is expressed in different cell types. An online version of the application can be found at https://tools.dice-database.org/celltypescore/ ." @default.
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- W2955997137 date "2019-06-27" @default.
- W2955997137 modified "2023-09-23" @default.
- W2955997137 title "Uncovering the cell type specificity of blood sample derived gene signatures using RNA expression data" @default.
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- W2955997137 doi "https://doi.org/10.1101/684159" @default.
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