FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2956036729> ?p ?o ?g. }

• W2956036729 endingPage "1900" @default.
• W2956036729 startingPage "1895" @default.
• W2956036729 abstract "Background: MicroRNAs (miRNAs) are non-coding RNAs that regulate multiple cellular processes during cancer progression, identified to be involved in tumorgenesis of several cancers including cancers of digestive system. However its role in gallbladder inflammatory disease (GID) and gallbladder cancer (GBC) has not been well documented. The present study was aimed to investigate the clinical significance of hsa-miRNA-335-5p (miR-335) in GBC and GID. Subjects and Methods: This prospective case control study, conducted from July 1, 2014 to December 1, 2017 in Era’s Lucknow Medical College & Hospital, India, evaluated miR-335 expression by real-time polymerase chain reaction. Hundred tissue samples GID (control; n=50) and GBC (case; n=50) were studied. Relative quantification of target miR-335 expression was examined using the comparative cycle threshold method. Their expression was correlated with different clinicopathological parameters. Fishers’ exact test, Student’s t-test, and Chi-square test were used as appropriate for data analysis. Kaplan-Meier methods were used to calculate overall and disease-free survival rate. Two sided P<0.05 was considered as significant. Results: miR-335 expression was found to be significantly low in GBC lesions when compared with GID lesions (P<0.001). The low expression level of miR-335 was correlated with histological grade (P=0.007), clinical stage (P<0.001), lymph node metastasis (P<0.001) and liver metastasis (P=0.016). Reduced expression of miRNA-335 was associated with a shorter median overall survival (7 months vs. 25 months) in GBC patients (P<0.001). Conclusions: Down regulation of miR-335 is associated with the severity of the disease and thus indicate that miR-335 expression may serve as prognostic marker for GBC." @default.
• W2956036729 created "2019-07-12" @default.
• W2956036729 creator A5018850665 @default.
• W2956036729 creator A5024327408 @default.
• W2956036729 creator A5033890490 @default.
• W2956036729 creator A5053710272 @default.
• W2956036729 creator A5058213743 @default.
• W2956036729 creator A5077523041 @default.
• W2956036729 creator A5088380208 @default.
• W2956036729 date "2019-06-01" @default.
• W2956036729 modified "2023-09-23" @default.
• W2956036729 title "Low Expression of MicroRNA335-5p Is Associated with Malignant Behavior of Gallbladder Cancer: A Clinicopathological Study" @default.
• W2956036729 cites W1665091651 @default.
• W2956036729 cites W1965371218 @default.
• W2956036729 cites W1967369606 @default.
• W2956036729 cites W1973329326 @default.
• W2956036729 cites W1978124522 @default.
• W2956036729 cites W1979206745 @default.
• W2956036729 cites W1985213644 @default.
• W2956036729 cites W1987004461 @default.
• W2956036729 cites W1988694445 @default.
• W2956036729 cites W1990044572 @default.
• W2956036729 cites W2001630698 @default.
• W2956036729 cites W2001707140 @default.
• W2956036729 cites W2027164278 @default.
• W2956036729 cites W2048948667 @default.
• W2956036729 cites W2058947870 @default.
• W2956036729 cites W2066523389 @default.
• W2956036729 cites W2075580956 @default.
• W2956036729 cites W2087350855 @default.
• W2956036729 cites W2099558746 @default.
• W2956036729 cites W2108786888 @default.
• W2956036729 cites W2124268899 @default.
• W2956036729 cites W2134197585 @default.
• W2956036729 cites W2147053822 @default.
• W2956036729 cites W2216055997 @default.
• W2956036729 cites W2225380553 @default.
• W2956036729 cites W2296419505 @default.
• W2956036729 cites W2486074980 @default.
• W2956036729 cites W2597872842 @default.
• W2956036729 cites W2612911334 @default.
• W2956036729 cites W2626167111 @default.
• W2956036729 cites W2736520162 @default.
• W2956036729 cites W2743377907 @default.
• W2956036729 cites W2766037981 @default.
• W2956036729 cites W2769573150 @default.
• W2956036729 cites W2774992434 @default.
• W2956036729 cites W2782704938 @default.
• W2956036729 cites W2908479231 @default.
• W2956036729 cites W3024609961 @default.
• W2956036729 cites W971209221 @default.
• W2956036729 doi "https://doi.org/10.31557/apjcp.2019.20.6.1895" @default.
• W2956036729 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7021618" @default.
• W2956036729 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31244315" @default.
• W2956036729 hasPublicationYear "2019" @default.
• W2956036729 type Work @default.
• W2956036729 sameAs 2956036729 @default.
• W2956036729 citedByCount "4" @default.
• W2956036729 countsByYear W29560367292019 @default.
• W2956036729 countsByYear W29560367292020 @default.
• W2956036729 countsByYear W29560367292022 @default.
• W2956036729 countsByYear W29560367292023 @default.
• W2956036729 crossrefType "journal-article" @default.
• W2956036729 hasAuthorship W2956036729A5018850665 @default.
• W2956036729 hasAuthorship W2956036729A5024327408 @default.
• W2956036729 hasAuthorship W2956036729A5033890490 @default.
• W2956036729 hasAuthorship W2956036729A5053710272 @default.
• W2956036729 hasAuthorship W2956036729A5058213743 @default.
• W2956036729 hasAuthorship W2956036729A5077523041 @default.
• W2956036729 hasAuthorship W2956036729A5088380208 @default.
• W2956036729 hasBestOaLocation W29560367291 @default.
• W2956036729 hasConcept C104317684 @default.
• W2956036729 hasConcept C10515644 @default.
• W2956036729 hasConcept C121608353 @default.
• W2956036729 hasConcept C126322002 @default.
• W2956036729 hasConcept C142724271 @default.
• W2956036729 hasConcept C143998085 @default.
• W2956036729 hasConcept C145059251 @default.
• W2956036729 hasConcept C146357865 @default.
• W2956036729 hasConcept C151730666 @default.
• W2956036729 hasConcept C2776534502 @default.
• W2956036729 hasConcept C2777148285 @default.
• W2956036729 hasConcept C2779013556 @default.
• W2956036729 hasConcept C55493867 @default.
• W2956036729 hasConcept C71924100 @default.
• W2956036729 hasConcept C86803240 @default.
• W2956036729 hasConcept C90924648 @default.
• W2956036729 hasConceptScore W2956036729C104317684 @default.
• W2956036729 hasConceptScore W2956036729C10515644 @default.
• W2956036729 hasConceptScore W2956036729C121608353 @default.
• W2956036729 hasConceptScore W2956036729C126322002 @default.
• W2956036729 hasConceptScore W2956036729C142724271 @default.
• W2956036729 hasConceptScore W2956036729C143998085 @default.
• W2956036729 hasConceptScore W2956036729C145059251 @default.
• W2956036729 hasConceptScore W2956036729C146357865 @default.
• W2956036729 hasConceptScore W2956036729C151730666 @default.
• W2956036729 hasConceptScore W2956036729C2776534502 @default.
• W2956036729 hasConceptScore W2956036729C2777148285 @default.

• next