FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2956041343> ?p ?o ?g. }

• W2956041343 abstract "The innate immune system is an evolutionarily conserved host defense system and is the first barrier to infection. The system utilizes genetically conserved receptors to identify the presence of microbial structures. Engagement of innate immune receptors by primarily by ligands that discriminate pathogens from the host activates programmed responses that limit pathogen expansion. Despite its ubiquitous nature, surprisingly DNA is a critical structure that triggers innate immune responses. Focusing on structural modifications or aberrant location of DNA, innate immune receptors identify physiologic stress. Inflammasomes and interferons are critical innate immune pathways that are activated by DNA. DNA binding proteins that tie recognition of DNA to both programmed responses have been identified, and their importance demonstrated in infection models. In this chapter, we discuss techniques to analyze AIM2 inflammasome and cGAS interferon activation by synthetic DNA and DNA viruses. We also discuss methods to measure the activity of these immune pathways." @default.
• W2956041343 created "2019-07-12" @default.
• W2956041343 creator A5012156872 @default.
• W2956041343 creator A5064509970 @default.
• W2956041343 date "2019-01-01" @default.
• W2956041343 modified "2023-09-27" @default.
• W2956041343 title "Assessment of inflammasome and type I IFN responses to DNA viruses and DNA PAMPS" @default.
• W2956041343 cites W1542158376 @default.
• W2956041343 cites W1561041814 @default.
• W2956041343 cites W1667606852 @default.
• W2956041343 cites W1820258609 @default.
• W2956041343 cites W1897605380 @default.
• W2956041343 cites W1968178474 @default.
• W2956041343 cites W1970436087 @default.
• W2956041343 cites W1984632540 @default.
• W2956041343 cites W2005359428 @default.
• W2956041343 cites W2009351870 @default.
• W2956041343 cites W2014094896 @default.
• W2956041343 cites W2016196756 @default.
• W2956041343 cites W2022273444 @default.
• W2956041343 cites W2029717255 @default.
• W2956041343 cites W2030611349 @default.
• W2956041343 cites W2034946303 @default.
• W2956041343 cites W2039390702 @default.
• W2956041343 cites W2042816890 @default.
• W2956041343 cites W2044210137 @default.
• W2956041343 cites W2047365750 @default.
• W2956041343 cites W2048226187 @default.
• W2956041343 cites W2056124534 @default.
• W2956041343 cites W2056810047 @default.
• W2956041343 cites W2085192138 @default.
• W2956041343 cites W2091144643 @default.
• W2956041343 cites W2095805777 @default.
• W2956041343 cites W2097787211 @default.
• W2956041343 cites W2099610218 @default.
• W2956041343 cites W2104195963 @default.
• W2956041343 cites W2109491705 @default.
• W2956041343 cites W2114085082 @default.
• W2956041343 cites W2116803339 @default.
• W2956041343 cites W2118451644 @default.
• W2956041343 cites W2123645680 @default.
• W2956041343 cites W2125845521 @default.
• W2956041343 cites W2127684626 @default.
• W2956041343 cites W2131617804 @default.
• W2956041343 cites W2134167421 @default.
• W2956041343 cites W2142433291 @default.
• W2956041343 cites W2145732011 @default.
• W2956041343 cites W2146122014 @default.
• W2956041343 cites W2148824237 @default.
• W2956041343 cites W2150157031 @default.
• W2956041343 cites W2154171253 @default.
• W2956041343 cites W2156301166 @default.
• W2956041343 cites W2157305255 @default.
• W2956041343 cites W2162735052 @default.
• W2956041343 cites W2278978291 @default.
• W2956041343 cites W2326661860 @default.
• W2956041343 cites W2522054313 @default.
• W2956041343 cites W2560067098 @default.
• W2956041343 cites W2604630852 @default.
• W2956041343 cites W2613314923 @default.
• W2956041343 cites W2619234348 @default.
• W2956041343 cites W2619425167 @default.
• W2956041343 doi "https://doi.org/10.1016/bs.mie.2019.05.008" @default.
• W2956041343 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31455531" @default.
• W2956041343 hasPublicationYear "2019" @default.
• W2956041343 type Work @default.
• W2956041343 sameAs 2956041343 @default.
• W2956041343 citedByCount "0" @default.
• W2956041343 crossrefType "book-chapter" @default.
• W2956041343 hasAuthorship W2956041343A5012156872 @default.
• W2956041343 hasAuthorship W2956041343A5064509970 @default.
• W2956041343 hasConcept C103474210 @default.
• W2956041343 hasConcept C111289621 @default.
• W2956041343 hasConcept C136449434 @default.
• W2956041343 hasConcept C170493617 @default.
• W2956041343 hasConcept C187831198 @default.
• W2956041343 hasConcept C188899842 @default.
• W2956041343 hasConcept C203014093 @default.
• W2956041343 hasConcept C2776178377 @default.
• W2956041343 hasConcept C2777209026 @default.
• W2956041343 hasConcept C2778278966 @default.
• W2956041343 hasConcept C54355233 @default.
• W2956041343 hasConcept C552990157 @default.
• W2956041343 hasConcept C86803240 @default.
• W2956041343 hasConcept C8891405 @default.
• W2956041343 hasConcept C95444343 @default.
• W2956041343 hasConceptScore W2956041343C103474210 @default.
• W2956041343 hasConceptScore W2956041343C111289621 @default.
• W2956041343 hasConceptScore W2956041343C136449434 @default.
• W2956041343 hasConceptScore W2956041343C170493617 @default.
• W2956041343 hasConceptScore W2956041343C187831198 @default.
• W2956041343 hasConceptScore W2956041343C188899842 @default.
• W2956041343 hasConceptScore W2956041343C203014093 @default.
• W2956041343 hasConceptScore W2956041343C2776178377 @default.
• W2956041343 hasConceptScore W2956041343C2777209026 @default.
• W2956041343 hasConceptScore W2956041343C2778278966 @default.
• W2956041343 hasConceptScore W2956041343C54355233 @default.
• W2956041343 hasConceptScore W2956041343C552990157 @default.
• W2956041343 hasConceptScore W2956041343C86803240 @default.
• W2956041343 hasConceptScore W2956041343C8891405 @default.

• next