Matches in SemOpenAlex for { <https://semopenalex.org/work/W2956082118> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2956082118 startingPage "1233" @default.
- W2956082118 abstract "The rationale for neoadjuvant chemoradiation therapy (Neo-CRT) and the definition of borderline resectable pancreatic cancer (BRPC) are still controversial. In particular, surgical treatment of BRPC with isolated venous vascular involvement (IVVI) is debatable.From January 2000 to December 2013, 84 patients diagnosed with BRPC according to NCCN guidelines were identified, and 70 patients were found to have BRPC with IVVI. We divided all 70 patients into 3 groups: surgery first without Neo-CRT (Group 1); pancreatectomy following Neo-CRT (Group 2); and no operation following Neo-CRT (Group 3). Patient characteristics including oncologic outcomes were analyzed for each of the 3 patients groups.Thirty-seven patients were female and 33 were male, with a mean age of 61.7 ± 9.74 years. Among the 70 BRPC patients with IVVI, 28 patients (40%) belonged to Group 1, 30 patients (42.9%) belonged to Group 2, and 12 patients (17.1%) belonged to Group 3. Pathological tumor size (P < 0.001), pT stage (P = 0.001), pTNM stage (P=0.002), combined vascular resection (P = 0.003), completeness of adjuvant therapy (P = 0.004) were found to be statistically significantly different between Groups 1 and 2. In addition, disease-free survival (P = 0.055) and disease-specific survival (DSS) (P=0.006) were improved in Group 2. Interestingly, when comparing DSS, there was no statistically significant difference between Groups 1 and 3 (P = 0.991).The clinical practice of pancreatectomy following Neo-CRT in BRPC with IVVI provided favorable oncologic outcomes. The effect of Neo-CRT in BRPC with IVVI may be multifactorial, providing proper patient selection, complete adjuvant chemotherapy, and potential therapeutic (downstaging) effect." @default.
- W2956082118 created "2019-07-12" @default.
- W2956082118 creator A5009999001 @default.
- W2956082118 creator A5010021409 @default.
- W2956082118 creator A5018158717 @default.
- W2956082118 creator A5023974220 @default.
- W2956082118 creator A5025462310 @default.
- W2956082118 creator A5042270068 @default.
- W2956082118 creator A5055502302 @default.
- W2956082118 creator A5059117938 @default.
- W2956082118 date "2015-01-01" @default.
- W2956082118 modified "2023-09-27" @default.
- W2956082118 title "The Role of Neoadjuvant Chemoradiation Therapy in Patients With Borderline Resectable Pancreatic Cancer With Isolated Venous Vascular Involvement" @default.
- W2956082118 hasPublicationYear "2015" @default.
- W2956082118 type Work @default.
- W2956082118 sameAs 2956082118 @default.
- W2956082118 citedByCount "0" @default.
- W2956082118 crossrefType "journal-article" @default.
- W2956082118 hasAuthorship W2956082118A5009999001 @default.
- W2956082118 hasAuthorship W2956082118A5010021409 @default.
- W2956082118 hasAuthorship W2956082118A5018158717 @default.
- W2956082118 hasAuthorship W2956082118A5023974220 @default.
- W2956082118 hasAuthorship W2956082118A5025462310 @default.
- W2956082118 hasAuthorship W2956082118A5042270068 @default.
- W2956082118 hasAuthorship W2956082118A5055502302 @default.
- W2956082118 hasAuthorship W2956082118A5059117938 @default.
- W2956082118 hasConcept C121608353 @default.
- W2956082118 hasConcept C126322002 @default.
- W2956082118 hasConcept C141071460 @default.
- W2956082118 hasConcept C146357865 @default.
- W2956082118 hasConcept C151730666 @default.
- W2956082118 hasConcept C207886595 @default.
- W2956082118 hasConcept C2777982462 @default.
- W2956082118 hasConcept C2778292576 @default.
- W2956082118 hasConcept C2778494859 @default.
- W2956082118 hasConcept C2778764654 @default.
- W2956082118 hasConcept C2780210213 @default.
- W2956082118 hasConcept C2780258809 @default.
- W2956082118 hasConcept C530470458 @default.
- W2956082118 hasConcept C71924100 @default.
- W2956082118 hasConcept C86803240 @default.
- W2956082118 hasConceptScore W2956082118C121608353 @default.
- W2956082118 hasConceptScore W2956082118C126322002 @default.
- W2956082118 hasConceptScore W2956082118C141071460 @default.
- W2956082118 hasConceptScore W2956082118C146357865 @default.
- W2956082118 hasConceptScore W2956082118C151730666 @default.
- W2956082118 hasConceptScore W2956082118C207886595 @default.
- W2956082118 hasConceptScore W2956082118C2777982462 @default.
- W2956082118 hasConceptScore W2956082118C2778292576 @default.
- W2956082118 hasConceptScore W2956082118C2778494859 @default.
- W2956082118 hasConceptScore W2956082118C2778764654 @default.
- W2956082118 hasConceptScore W2956082118C2780210213 @default.
- W2956082118 hasConceptScore W2956082118C2780258809 @default.
- W2956082118 hasConceptScore W2956082118C530470458 @default.
- W2956082118 hasConceptScore W2956082118C71924100 @default.
- W2956082118 hasConceptScore W2956082118C86803240 @default.
- W2956082118 hasIssue "31" @default.
- W2956082118 hasLocation W29560821181 @default.
- W2956082118 hasOpenAccess W2956082118 @default.
- W2956082118 hasPrimaryLocation W29560821181 @default.
- W2956082118 hasRelatedWork W1530926240 @default.
- W2956082118 hasRelatedWork W1964601821 @default.
- W2956082118 hasRelatedWork W1993645230 @default.
- W2956082118 hasRelatedWork W1999139441 @default.
- W2956082118 hasRelatedWork W2058972164 @default.
- W2956082118 hasRelatedWork W2340263548 @default.
- W2956082118 hasRelatedWork W2362907651 @default.
- W2956082118 hasRelatedWork W2589544633 @default.
- W2956082118 hasRelatedWork W2738176961 @default.
- W2956082118 hasRelatedWork W2765938006 @default.
- W2956082118 hasRelatedWork W2885486990 @default.
- W2956082118 hasRelatedWork W2894792945 @default.
- W2956082118 hasRelatedWork W2942700362 @default.
- W2956082118 hasRelatedWork W3024263598 @default.
- W2956082118 hasRelatedWork W3058386207 @default.
- W2956082118 hasRelatedWork W3167469906 @default.
- W2956082118 hasRelatedWork W3174488439 @default.
- W2956082118 hasRelatedWork W3176951779 @default.
- W2956082118 hasRelatedWork W3195726699 @default.
- W2956082118 hasRelatedWork W2140765857 @default.
- W2956082118 hasVolume "94" @default.
- W2956082118 isParatext "false" @default.
- W2956082118 isRetracted "false" @default.
- W2956082118 magId "2956082118" @default.
- W2956082118 workType "article" @default.