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• W2956085092 abstract "Mathematical models and computer simulations have the great potential to substantially increase our understanding of the biophysical behavior of the neuromuscular system. This, however, requires detailed multiscale, and multiphysics models. Once validated, such models allow systematic in silico investigations that are not necessarily feasible within experiments and, therefore, have the ability to provide valuable insights into the complex interrelations within the healthy system and for pathological conditions. Most of the existing models focus on individual parts of the neuromuscular system and do not consider the neuromuscular system as an integrated physiological system. Hence, the aim of this advanced review is to facilitate the prospective development of detailed biophysical models of the entire neuromuscular system. For this purpose, this review is subdivided into three parts. The first part introduces the key anatomical and physiological aspects of the healthy neuromuscular system necessary for modeling the neuromuscular system. The second part provides an overview on state-of-the-art modeling approaches representing all major components of the neuromuscular system on different time and length scales. Within the last part, a specific multiscale neuromuscular system model is introduced. The integrated system model combines existing models of the motor neuron pool, of the sensory system and of a multiscale model describing the mechanical behavior of skeletal muscles. Since many sub-models are based on strictly biophysical modeling approaches, it closely represents the underlying physiological system and thus could be employed as starting point for further improvements and future developments. This article is categorized under: Physiology > Mammalian Physiology in Health and Disease Analytical and Computational Methods > Computational Methods Models of Systems Properties and Processes > Organ, Tissue, and Physiological Models." @default.
• W2956085092 created "2019-07-12" @default.
• W2956085092 creator A5008095093 @default.
• W2956085092 creator A5016387481 @default.
• W2956085092 creator A5021841828 @default.
• W2956085092 creator A5032001702 @default.
• W2956085092 creator A5081333112 @default.
• W2956085092 date "2019-06-24" @default.
• W2956085092 modified "2023-10-03" @default.
• W2956085092 title "Multiscale modeling of the neuromuscular system: Coupling neurophysiology and skeletal muscle mechanics" @default.
• W2956085092 cites W1481508412 @default.
• W2956085092 cites W1498566120 @default.
• W2956085092 cites W1514261135 @default.
• W2956085092 cites W1516920781 @default.
• W2956085092 cites W1519451866 @default.
• W2956085092 cites W1541067914 @default.
• W2956085092 cites W1547857986 @default.
• W2956085092 cites W161981996 @default.
• W2956085092 cites W1735445987 @default.
• W2956085092 cites W1809394698 @default.
• W2956085092 cites W1853006911 @default.
• W2956085092 cites W1861912616 @default.
• W2956085092 cites W187864750 @default.
• W2956085092 cites W1901823973 @default.
• W2956085092 cites W1951774030 @default.
• W2956085092 cites W1964859063 @default.
• W2956085092 cites W1965883224 @default.
• W2956085092 cites W1967113483 @default.
• W2956085092 cites W1967682606 @default.
• W2956085092 cites W1968733302 @default.
• W2956085092 cites W1970219880 @default.
• W2956085092 cites W1970977697 @default.
• W2956085092 cites W1971828667 @default.
• W2956085092 cites W1971990609 @default.
• W2956085092 cites W1972694197 @default.
• W2956085092 cites W1973292561 @default.
• W2956085092 cites W1974668501 @default.
• W2956085092 cites W1975714515 @default.
• W2956085092 cites W1976812519 @default.
• W2956085092 cites W1978226545 @default.
• W2956085092 cites W1979084896 @default.
• W2956085092 cites W1979507072 @default.
• W2956085092 cites W1979826626 @default.
• W2956085092 cites W1982446556 @default.
• W2956085092 cites W1983821055 @default.
• W2956085092 cites W1985940938 @default.
• W2956085092 cites W1986214110 @default.
• W2956085092 cites W1986253312 @default.
• W2956085092 cites W1986354109 @default.
• W2956085092 cites W1986517532 @default.
• W2956085092 cites W1988003441 @default.
• W2956085092 cites W1988961822 @default.
• W2956085092 cites W1990930156 @default.
• W2956085092 cites W1992121070 @default.
• W2956085092 cites W1993540370 @default.
• W2956085092 cites W1993978782 @default.
• W2956085092 cites W1994455838 @default.
• W2956085092 cites W1994732710 @default.
• W2956085092 cites W1995086479 @default.
• W2956085092 cites W1995322222 @default.
• W2956085092 cites W1995339557 @default.
• W2956085092 cites W1996060061 @default.
• W2956085092 cites W1996078735 @default.
• W2956085092 cites W1998082644 @default.
• W2956085092 cites W1998331641 @default.
• W2956085092 cites W1999344755 @default.
• W2956085092 cites W1999879638 @default.
• W2956085092 cites W2000533386 @default.
• W2956085092 cites W2001144437 @default.
• W2956085092 cites W2001370494 @default.
• W2956085092 cites W2001414779 @default.
• W2956085092 cites W2001616350 @default.
• W2956085092 cites W2002208222 @default.
• W2956085092 cites W2002478801 @default.
• W2956085092 cites W2003291100 @default.
• W2956085092 cites W2003313420 @default.
• W2956085092 cites W2004737679 @default.
• W2956085092 cites W2005092540 @default.
• W2956085092 cites W2005329268 @default.
• W2956085092 cites W2005995324 @default.
• W2956085092 cites W2008089463 @default.
• W2956085092 cites W2009096188 @default.
• W2956085092 cites W2011647953 @default.
• W2956085092 cites W2013627431 @default.
• W2956085092 cites W2014574071 @default.
• W2956085092 cites W2015179427 @default.
• W2956085092 cites W2016368406 @default.
• W2956085092 cites W2017226208 @default.
• W2956085092 cites W2018231630 @default.
• W2956085092 cites W2020077459 @default.
• W2956085092 cites W2020271815 @default.
• W2956085092 cites W2020983843 @default.
• W2956085092 cites W2022019553 @default.
• W2956085092 cites W2028565798 @default.
• W2956085092 cites W2031639005 @default.
• W2956085092 cites W2031856781 @default.
• W2956085092 cites W2033169946 @default.
• W2956085092 cites W2034512096 @default.
• W2956085092 cites W2036986117 @default.
• W2956085092 cites W2037576214 @default.

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