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- W2956089324 abstract "Colorectal surgery (CS) is known for its inherent high risk of surgical site infection, estimated between 20%-30%. This study was thus designed to understand risk of infection types (deep vs superficial vs organ/space) and associated costs for these patients. A retrospective study of patients undergoing CS between 2014 and 2017 was conducted using IBM® MarketScan® Commercial, Multi-State Medicaid and Medicare Supplemental databases. All patients had continuous enrollment for ≥12 months before and 6 months after CS. Patients were categorized by demographic and clinical comorbidities as per the 31 domains of the Elixhauser Comorbidity Index. The outcome were new diagnoses of infection, categorized as organ/space, deep, or superficial within 6 months of CS. Logistic regression models were evaluated to determine variables associated with infection. Generalized linear regression models were built and adjusted total payments due to infection by category were estimated using least squares means. All payments were adjusted to 2017 consumer price-index. A total of 83,691 patients were included in the analysis, with mean age 56 years (SD:17.38), 53.6% female, 27.4% cancer patients of which 5.3% with metastatic neoplasms, 21.5% Medicare and 21.60% Medicaid (all others commercially insured), 78.8% with no post-CS infection. Of the 21.1% patients with infection, > 84% were identified within 60 days of CS. Post-surgical infection included 9.0% organ/space, 1.0% deep, 0.8% for both organ/space and deep and 10.4% superficial cases. Adjusted total payments in patients with commercial insurance ranged from $154,332 (95% CI: $149,353-$159,478) for superficial to $185,435 (95% CI: $163,586-$210,202) for deep infection between CS and two-years post. Key risk factors for infection included weight loss and fluid and electrolyte disorder. More than 21% patients suffer from post-CS infection, nearly 51% of which affected by deep or organ/space infection. Ongoing research include understanding patient risk profiles and developing risk mitigation strategies." @default.
- W2956089324 created "2019-07-12" @default.
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- W2956089324 date "2019-05-01" @default.
- W2956089324 modified "2023-10-16" @default.
- W2956089324 title "PSU26 COLORECTAL SURGERY: RISK AND BURDEN OF POST-SURGICAL ORGAN/SPACE, DEEP AND SUPERFICIAL INFECTION" @default.
- W2956089324 doi "https://doi.org/10.1016/j.jval.2019.04.1806" @default.
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