FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2956104860> ?p ?o ?g. }

• W2956104860 endingPage "982" @default.
• W2956104860 startingPage "979" @default.
• W2956104860 abstract "Congenital long QT syndrome (LQTS) is a cardiac channelopathy that leads to the prolongation of the QT interval. This prolongation can lead to ventricular tachyarrhythmia, syncope, and sudden cardiac death. There are various types of LQTS. Treatment of LQT1 and LQT2 is mainly based on antiadrenergic therapy. LQT3, on the other hand, is a result of a mutation of the SCN5A gene, which encodes the sodium channels. In this type, patients are sensitive to vagal stimuli and episodes tend to occur at rest. Sodium channel blocking compounds, such as ranolazine, mexiletine, and flecainide, have been found to be effective in selective mutations.In this case report, we report the case of a child with congenital LQT3 (V411M) who presented first with sudden cardiac death and three weeks later with an implantable cardioverter defibrillator storm. Knowing the specific mutation and understanding the mechanism at the molecular level through an in vitro study yielded a clinically meaningful result. The patient's arrhythmia burden was totally eliminated following successful treatment with flecainide." @default.
• W2956104860 created "2019-07-12" @default.
• W2956104860 creator A5027217970 @default.
• W2956104860 creator A5035911633 @default.
• W2956104860 creator A5041818873 @default.
• W2956104860 creator A5063252239 @default.
• W2956104860 creator A5080055220 @default.
• W2956104860 creator A5081253066 @default.
• W2956104860 date "2019-07-30" @default.
• W2956104860 modified "2023-10-03" @default.
• W2956104860 title "Specific Therapy Based on the Genotype in a Malignant Form of Long QT3, Carrying the V411M Mutation" @default.
• W2956104860 cites W1583392605 @default.
• W2956104860 cites W1608629933 @default.
• W2956104860 cites W1947626002 @default.
• W2956104860 cites W1987908892 @default.
• W2956104860 cites W1996802734 @default.
• W2956104860 cites W2002374666 @default.
• W2956104860 cites W2005240974 @default.
• W2956104860 cites W2010248111 @default.
• W2956104860 cites W2027684356 @default.
• W2956104860 cites W2033635664 @default.
• W2956104860 cites W2072732939 @default.
• W2956104860 cites W2081072082 @default.
• W2956104860 cites W2084451187 @default.
• W2956104860 cites W2085007473 @default.
• W2956104860 cites W2090086025 @default.
• W2956104860 cites W2095581992 @default.
• W2956104860 cites W2097912415 @default.
• W2956104860 cites W2106326075 @default.
• W2956104860 cites W2107525942 @default.
• W2956104860 cites W2110639216 @default.
• W2956104860 cites W2124865340 @default.
• W2956104860 cites W2125571983 @default.
• W2956104860 cites W2896578421 @default.
• W2956104860 cites W2898228556 @default.
• W2956104860 doi "https://doi.org/10.1536/ihj.18-705" @default.
• W2956104860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31257342" @default.
• W2956104860 hasPublicationYear "2019" @default.
• W2956104860 type Work @default.
• W2956104860 sameAs 2956104860 @default.
• W2956104860 citedByCount "6" @default.
• W2956104860 countsByYear W29561048602020 @default.
• W2956104860 countsByYear W29561048602021 @default.
• W2956104860 crossrefType "journal-article" @default.
• W2956104860 hasAuthorship W2956104860A5027217970 @default.
• W2956104860 hasAuthorship W2956104860A5035911633 @default.
• W2956104860 hasAuthorship W2956104860A5041818873 @default.
• W2956104860 hasAuthorship W2956104860A5063252239 @default.
• W2956104860 hasAuthorship W2956104860A5080055220 @default.
• W2956104860 hasAuthorship W2956104860A5081253066 @default.
• W2956104860 hasBestOaLocation W29561048601 @default.
• W2956104860 hasConcept C118441451 @default.
• W2956104860 hasConcept C126322002 @default.
• W2956104860 hasConcept C164705383 @default.
• W2956104860 hasConcept C178790620 @default.
• W2956104860 hasConcept C185592680 @default.
• W2956104860 hasConcept C2775935837 @default.
• W2956104860 hasConcept C2776414672 @default.
• W2956104860 hasConcept C2777561782 @default.
• W2956104860 hasConcept C2777989426 @default.
• W2956104860 hasConcept C2779161974 @default.
• W2956104860 hasConcept C2779177932 @default.
• W2956104860 hasConcept C2779703243 @default.
• W2956104860 hasConcept C2779837460 @default.
• W2956104860 hasConcept C2993353509 @default.
• W2956104860 hasConcept C50952357 @default.
• W2956104860 hasConcept C537181965 @default.
• W2956104860 hasConcept C71924100 @default.
• W2956104860 hasConceptScore W2956104860C118441451 @default.
• W2956104860 hasConceptScore W2956104860C126322002 @default.
• W2956104860 hasConceptScore W2956104860C164705383 @default.
• W2956104860 hasConceptScore W2956104860C178790620 @default.
• W2956104860 hasConceptScore W2956104860C185592680 @default.
• W2956104860 hasConceptScore W2956104860C2775935837 @default.
• W2956104860 hasConceptScore W2956104860C2776414672 @default.
• W2956104860 hasConceptScore W2956104860C2777561782 @default.
• W2956104860 hasConceptScore W2956104860C2777989426 @default.
• W2956104860 hasConceptScore W2956104860C2779161974 @default.
• W2956104860 hasConceptScore W2956104860C2779177932 @default.
• W2956104860 hasConceptScore W2956104860C2779703243 @default.
• W2956104860 hasConceptScore W2956104860C2779837460 @default.
• W2956104860 hasConceptScore W2956104860C2993353509 @default.
• W2956104860 hasConceptScore W2956104860C50952357 @default.
• W2956104860 hasConceptScore W2956104860C537181965 @default.
• W2956104860 hasConceptScore W2956104860C71924100 @default.
• W2956104860 hasIssue "4" @default.
• W2956104860 hasLocation W29561048601 @default.
• W2956104860 hasLocation W29561048602 @default.
• W2956104860 hasOpenAccess W2956104860 @default.
• W2956104860 hasPrimaryLocation W29561048601 @default.
• W2956104860 hasRelatedWork W2017615140 @default.
• W2956104860 hasRelatedWork W2146570555 @default.
• W2956104860 hasRelatedWork W2406017310 @default.
• W2956104860 hasRelatedWork W2800009521 @default.
• W2956104860 hasRelatedWork W2800767199 @default.
• W2956104860 hasRelatedWork W2956104860 @default.
• W2956104860 hasRelatedWork W3111943800 @default.
• W2956104860 hasRelatedWork W3182597380 @default.

• next