Matches in SemOpenAlex for { <https://semopenalex.org/work/W2956112079> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2956112079 endingPage "813" @default.
- W2956112079 startingPage "807" @default.
- W2956112079 abstract "MicroRNAs are highly conserved endogenous small noncoding RNAs and demonstrated to play important roles in the metastatic cascade of papillary thyroid carcinoma (PTC), including the process of anoikis resistance. In this study, the correlation between miRNA-363-3p (miR-363-3p) expression and PTC metastasis was analyzed based on clinical data, and the effect and related mechanism of miR-363-3p on anoikis resistance in B-CPAP cells were further investigated. First, miR-363-3p was found to be down-regulated in PTC tissue, which was correlated with the advanced clinical stage and lymph node (LN) metastasis. Then, functional study revealed that miR-363-3p was also down-regulated in B-CPAP cells compared with that in thyroid epithelial Nthy-ori3-1 cells, and miR-363-3p transfection could suppress anoikis resistance of B-CPAP cells. Finally, integrin alpha 6 (ITGA6) was validated as the target gene of miR-363-3p, and restoration of ITGA6 expression attenuated miR-363-3p's inhibitory effect on anoikis resistance in B-CPAP cells. These findings contribute to understand the role of miR-363-3p in the metastatic cascade of PTC and suggest the potential clinical value of miR-363-3p for the prevention of PTC metastasis." @default.
- W2956112079 created "2019-07-12" @default.
- W2956112079 creator A5030536674 @default.
- W2956112079 creator A5056366493 @default.
- W2956112079 creator A5062302432 @default.
- W2956112079 creator A5073763798 @default.
- W2956112079 date "2019-06-01" @default.
- W2956112079 modified "2023-10-16" @default.
- W2956112079 title "MicroRNA-363-3p suppresses anoikis resistance in human papillary thyroid carcinoma via targeting integrin alpha 6" @default.
- W2956112079 cites W1974254202 @default.
- W2956112079 cites W1987201457 @default.
- W2956112079 cites W2039246912 @default.
- W2956112079 cites W2059117644 @default.
- W2956112079 cites W2071123870 @default.
- W2956112079 cites W2109920372 @default.
- W2956112079 cites W2131717149 @default.
- W2956112079 cites W2138362890 @default.
- W2956112079 cites W2331645092 @default.
- W2956112079 cites W2336945046 @default.
- W2956112079 cites W2519598273 @default.
- W2956112079 cites W2547394998 @default.
- W2956112079 cites W2595446467 @default.
- W2956112079 cites W2598018000 @default.
- W2956112079 cites W2625721819 @default.
- W2956112079 cites W2627060047 @default.
- W2956112079 cites W2789281724 @default.
- W2956112079 cites W2792194655 @default.
- W2956112079 cites W2808927630 @default.
- W2956112079 cites W2891651490 @default.
- W2956112079 cites W2917837889 @default.
- W2956112079 doi "https://doi.org/10.1093/abbs/gmz066" @default.
- W2956112079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31257410" @default.
- W2956112079 hasPublicationYear "2019" @default.
- W2956112079 type Work @default.
- W2956112079 sameAs 2956112079 @default.
- W2956112079 citedByCount "14" @default.
- W2956112079 countsByYear W29561120792020 @default.
- W2956112079 countsByYear W29561120792021 @default.
- W2956112079 countsByYear W29561120792022 @default.
- W2956112079 countsByYear W29561120792023 @default.
- W2956112079 crossrefType "journal-article" @default.
- W2956112079 hasAuthorship W2956112079A5030536674 @default.
- W2956112079 hasAuthorship W2956112079A5056366493 @default.
- W2956112079 hasAuthorship W2956112079A5062302432 @default.
- W2956112079 hasAuthorship W2956112079A5073763798 @default.
- W2956112079 hasConcept C104317684 @default.
- W2956112079 hasConcept C121608353 @default.
- W2956112079 hasConcept C126322002 @default.
- W2956112079 hasConcept C145059251 @default.
- W2956112079 hasConcept C152000582 @default.
- W2956112079 hasConcept C2779013556 @default.
- W2956112079 hasConcept C2993294228 @default.
- W2956112079 hasConcept C502942594 @default.
- W2956112079 hasConcept C526584372 @default.
- W2956112079 hasConcept C54009773 @default.
- W2956112079 hasConcept C54355233 @default.
- W2956112079 hasConcept C71924100 @default.
- W2956112079 hasConcept C81885089 @default.
- W2956112079 hasConcept C86803240 @default.
- W2956112079 hasConceptScore W2956112079C104317684 @default.
- W2956112079 hasConceptScore W2956112079C121608353 @default.
- W2956112079 hasConceptScore W2956112079C126322002 @default.
- W2956112079 hasConceptScore W2956112079C145059251 @default.
- W2956112079 hasConceptScore W2956112079C152000582 @default.
- W2956112079 hasConceptScore W2956112079C2779013556 @default.
- W2956112079 hasConceptScore W2956112079C2993294228 @default.
- W2956112079 hasConceptScore W2956112079C502942594 @default.
- W2956112079 hasConceptScore W2956112079C526584372 @default.
- W2956112079 hasConceptScore W2956112079C54009773 @default.
- W2956112079 hasConceptScore W2956112079C54355233 @default.
- W2956112079 hasConceptScore W2956112079C71924100 @default.
- W2956112079 hasConceptScore W2956112079C81885089 @default.
- W2956112079 hasConceptScore W2956112079C86803240 @default.
- W2956112079 hasIssue "8" @default.
- W2956112079 hasLocation W29561120791 @default.
- W2956112079 hasLocation W29561120792 @default.
- W2956112079 hasOpenAccess W2956112079 @default.
- W2956112079 hasPrimaryLocation W29561120791 @default.
- W2956112079 hasRelatedWork W1817878660 @default.
- W2956112079 hasRelatedWork W2042559265 @default.
- W2956112079 hasRelatedWork W2594860815 @default.
- W2956112079 hasRelatedWork W2602917813 @default.
- W2956112079 hasRelatedWork W2604422439 @default.
- W2956112079 hasRelatedWork W2607027744 @default.
- W2956112079 hasRelatedWork W2748952813 @default.
- W2956112079 hasRelatedWork W2946886290 @default.
- W2956112079 hasRelatedWork W3117169687 @default.
- W2956112079 hasRelatedWork W3136905963 @default.
- W2956112079 hasVolume "51" @default.
- W2956112079 isParatext "false" @default.
- W2956112079 isRetracted "false" @default.
- W2956112079 magId "2956112079" @default.
- W2956112079 workType "article" @default.