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• W2956124935 abstract "BACKGROUND The employment of the O-arm for intraoperative localization of deep brain stimulation (DBS) leads has been shown to be feasible and effective. However, partial volume artifacts impede the determination of individual electrode contacts and thus allow only an indirect approximation of each contact's localization. OBJECTIVE To reduce the partial volume artifacts by means of high-resolution (HiRes) reconstruction of O-arm data and thus allow more accurate predictions with regard to the positioning and orientation of individual DBS contacts. METHODS Following intraoperative flat-panel computed tomography, the O-arm raw data were reconstructed with a resolution of 0.2 mm × 0.2 mm × 0.2 mm. The geometric integrity of HiRes reconstructions was assessed via landmark transformation. Using a phantom, resolutions of both reconstruction modalities were then evaluated by means of the modulation transfer function (MTF). Finally, directional and nondirectional leads were compared visually to analyze the delineation of individual electrode contacts. RESULTS With a mean accuracy of 0.56 mm ± 0.12 mm, geometric integrity remained intact during HiRes reconstruction. Analysis of HiRes reconstruction resolution yielded a 47.7% increase of the 10% MTF in comparison to conventional postprocessing. Reduction of partial volume artifacts yielded strong contrasts of electrode compartments and allowed direct identification of individual contacts as well as localization of the X-ray marker on directional leads. CONCLUSION HiRes reconstruction of O-arm data allows an effective reduction of partial volume artifacts to such an extent that a delineation of individual contacts across single DBS leads is possible without requiring increases in radiation dose." @default.
• W2956124935 created "2019-07-12" @default.
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• W2956124935 date "2019-06-24" @default.
• W2956124935 modified "2023-09-23" @default.
• W2956124935 title "High-Resolution O-Arm Data Reconstruction for Optimized Intraoperative Imaging of Deep Brain Stimulation Leads: A Preclinical Study" @default.
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• W2956124935 doi "https://doi.org/10.1093/ons/opz175" @default.
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