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• W2956171667 abstract "Abstract Background Neonatal hypoglycemia is a common and treatable risk factor for neurological impairment. Real‐time continuous glucose monitoring ( RT ‐ CGM ) can show glucose concentration in real time. Using an RT ‐ CGM alarm, physicians can be alerted and intervene in hypoglycemia. No reports, however, have evaluated the reliability of RT ‐ CGM at low glucose levels in infants. This study therefore investigated the difference between blood glucose ( BG ) and RT ‐ CGM sensor data at low glucose levels and assessed the optimum method of using a hypoglycemic alarm in infants. Methods We enrolled infants whose glycemic management was difficult. We calculated the mean absolute difference ( MAD ) and mean absolute relative difference ( MARD ) between BG and RT ‐ CGM sensor data. We compared the MAD and MARD between the low BG fluctuation and high BG fluctuation groups. Results We used RT ‐ CGM for 12 patients (29 times) and investigated 448 pairs of BG and RT ‐ CGM sensor data. The MAD between these pairs was 9.3 ± 8.9 mg/ dL , and the MARD was 11.5%. The MAD at low glucose was 7.7 ± 6.0 mg/ dL , and the MARD was 16.2%. The MAD and MARD were 6.8 ± 5.4 mg/ dL and 7.8% in the low fluctuation group and 10.1 ± 9.5 mg/ dL and 12.7% in the high fluctuation group, respectively. Conclusions The difference between BG and RT ‐ CGM sensor data changes with the degree of fluctuation in BG . When physicians set the hypoglycemic alarm, consideration of this difference and a change in the alarm setting according to the degree of fluctuation in BG may be useful." @default.
• W2956171667 created "2019-07-23" @default.
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• W2956171667 date "2019-10-01" @default.
• W2956171667 modified "2023-09-26" @default.
• W2956171667 title "Reliability of real‐time continuous glucose monitoring in infants" @default.
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• W2956171667 doi "https://doi.org/10.1111/ped.13961" @default.
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