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• W2956185610 startingPage "119" @default.
• W2956185610 abstract "The field of extracellular vesicles is growing exponentially because of the important role that these extracellular organelles had on cell to cell communication, triggering a large number of review compilations focusing on different aspects of their biology. Although their importance as effectors or potential biomarkers is well covered, the highlight of extracellular vesicles as carriers of active enzymes which have the capability to transform the surrounding media is less covered by bibliographic studies. In the present review, we focus our attention on enzymatic activity carried by vesicles, with special attention on their contribution to liver conditions. Extracellular vesicles are circulating membrane-bound entities, characterized by a specific cargo. This cargo depends on the parental cell and the stimulus that triggers their release. Interestingly, the cargo includes active enzymes which had the ability of transforming the extracellular environment. Among them, extracellular vesicles derived from hepatocytes harbor specific liver enzymes that may cause an impact in the surrounds and target cells. In this review, we summarize different active enzymes described in extracellular vesicles and we focus on enzymatic activities associated to liver damage. Since their release increases under liver damage conditions, their activity impact could play a role in the pathogenesis of liver and liver-associated diseases. Numerous examples in different liver conditions provided evidence of the potential of extracellular vesicles as therapeutic targets." @default.
• W2956185610 created "2019-07-23" @default.
• W2956185610 creator A5028410310 @default.
• W2956185610 creator A5054735287 @default.
• W2956185610 creator A5068392063 @default.
• W2956185610 date "2019-07-17" @default.
• W2956185610 modified "2023-09-27" @default.
• W2956185610 title "Metabolic Nano-Machines: Extracellular Vesicles Containing Active Enzymes and Their Contribution to Liver Diseases" @default.
• W2956185610 cites W1066172147 @default.
• W2956185610 cites W125202112 @default.
• W2956185610 cites W1467572300 @default.
• W2956185610 cites W1487818015 @default.
• W2956185610 cites W1538384004 @default.
• W2956185610 cites W1543624067 @default.
• W2956185610 cites W1594863916 @default.
• W2956185610 cites W1651376769 @default.
• W2956185610 cites W1792460785 @default.
• W2956185610 cites W1915536483 @default.
• W2956185610 cites W1922364744 @default.
• W2956185610 cites W1967367827 @default.
• W2956185610 cites W1968928247 @default.
• W2956185610 cites W1969264414 @default.
• W2956185610 cites W1970241042 @default.
• W2956185610 cites W1981420342 @default.
• W2956185610 cites W1982533264 @default.
• W2956185610 cites W1986986277 @default.
• W2956185610 cites W1992031993 @default.
• W2956185610 cites W1996095828 @default.
• W2956185610 cites W2005993715 @default.
• W2956185610 cites W2011594621 @default.
• W2956185610 cites W2026320014 @default.
• W2956185610 cites W2032009734 @default.
• W2956185610 cites W2034005055 @default.
• W2956185610 cites W2034566612 @default.
• W2956185610 cites W2037484272 @default.
• W2956185610 cites W2043359720 @default.
• W2956185610 cites W2048883725 @default.
• W2956185610 cites W2050230226 @default.
• W2956185610 cites W2054546147 @default.
• W2956185610 cites W2055313665 @default.
• W2956185610 cites W2059435371 @default.
• W2956185610 cites W2062984171 @default.
• W2956185610 cites W2066432115 @default.
• W2956185610 cites W2067510355 @default.
• W2956185610 cites W2069412624 @default.
• W2956185610 cites W2078142549 @default.
• W2956185610 cites W2080879611 @default.
• W2956185610 cites W2083457479 @default.
• W2956185610 cites W2087550627 @default.
• W2956185610 cites W2090597108 @default.
• W2956185610 cites W2090803966 @default.
• W2956185610 cites W2099369804 @default.
• W2956185610 cites W2099628752 @default.
• W2956185610 cites W2109203664 @default.
• W2956185610 cites W2114443210 @default.
• W2956185610 cites W2115212312 @default.
• W2956185610 cites W2117446864 @default.
• W2956185610 cites W2121354606 @default.
• W2956185610 cites W2124750332 @default.
• W2956185610 cites W2127312775 @default.
• W2956185610 cites W2128891846 @default.
• W2956185610 cites W2132063970 @default.
• W2956185610 cites W2132603657 @default.
• W2956185610 cites W2138011807 @default.
• W2956185610 cites W2150892054 @default.
• W2956185610 cites W2153092839 @default.
• W2956185610 cites W2153733800 @default.
• W2956185610 cites W2154215235 @default.
• W2956185610 cites W2155335820 @default.
• W2956185610 cites W2155366992 @default.
• W2956185610 cites W2159114297 @default.
• W2956185610 cites W2161672948 @default.
• W2956185610 cites W2173706466 @default.
• W2956185610 cites W2183133882 @default.
• W2956185610 cites W2205677430 @default.
• W2956185610 cites W2298244104 @default.
• W2956185610 cites W2330004628 @default.
• W2956185610 cites W2371948111 @default.
• W2956185610 cites W2527999548 @default.
• W2956185610 cites W2534115969 @default.
• W2956185610 cites W2553919773 @default.
• W2956185610 cites W2561051704 @default.
• W2956185610 cites W2588587410 @default.
• W2956185610 cites W2606527666 @default.
• W2956185610 cites W2609904336 @default.
• W2956185610 cites W2725006904 @default.
• W2956185610 cites W2726430797 @default.
• W2956185610 cites W2736062522 @default.
• W2956185610 cites W2737895852 @default.
• W2956185610 cites W2740984393 @default.
• W2956185610 cites W2742463903 @default.
• W2956185610 cites W2752309600 @default.
• W2956185610 cites W2765824811 @default.
• W2956185610 cites W2767164985 @default.
• W2956185610 cites W2774967673 @default.
• W2956185610 cites W2785791389 @default.
• W2956185610 cites W2789654958 @default.
• W2956185610 cites W2814481017 @default.

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