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- W2956306002 abstract "Lung involvement is a common complication of inflammatory myopathies (IM) and mixed connective tissue disease (MCTD). Involvement of upper airway muscles, diaphragms, and other respiratory muscles can respectively cause obstructive sleep apnea and ventilatory failure, which may require intensive immunosuppressive therapy and noninvasive ventilatory support. Interstitial lung disease (ILD) is related to increased morbidity and mortality, and is the most common form of pulmonary involvement in patients with IM and MCTD. ILD is particularly associated to various specific myositis antibodies and is the hallmark of some IM phenotypes, such as the antisynthetase and anti-MDA5 syndrome. In this chapter, we focus on the current knowledge about lung involvement associated with IM and MCTD, with more attention to delineate and describe clinical ILD features and management linked to different IM subsets." @default.
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- W2956306002 date "2019-09-01" @default.
- W2956306002 modified "2023-09-27" @default.
- W2956306002 title "Interstitial lung disease associated with anti-PM-Scl antibody: A single center experience" @default.
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- W2956306002 doi "https://doi.org/10.1016/j.autrev.2019.102355" @default.
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