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• W2956355544 abstract "Abstract In the search of a better enzyme therapy in Pompe disease, the conjugation of mannose 6‐phosphonates to the recombinant enzyme appeared as an enhancer of its efficacy. Here, we demonstrated that the increased efficacy of the conjugated enzyme is partly due to a higher intracellular maturation because of its insensitiveness to acid phosphatases during the routing to lysosomes." @default.
• W2956355544 created "2019-07-23" @default.
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• W2956355544 date "2019-07-10" @default.
• W2956355544 modified "2023-10-03" @default.
• W2956355544 title "Mannose 6‐phosphonate labelling: A key for processing the therapeutic enzyme in Pompe disease" @default.
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• W2956355544 doi "https://doi.org/10.1111/jcmm.14516" @default.
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