Matches in SemOpenAlex for { <https://semopenalex.org/work/W29563716> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W29563716 endingPage "406" @default.
- W29563716 startingPage "401" @default.
- W29563716 abstract "Vaccinia-virus (VV) recombinants encoding either the nucleocapsid (N) or the spike (S) protein of MHV-JHM were constructed to study the role of the immune reponse against defined coronavirus antigens. For the S-protein, a fusogenic (Sfus+) or non fusogenic variant (Sfus-) of the gene was inserted into the VV genome. A strong protection against acute encephalomyelitis (AE) was mediated in Lewis rats which were immunized by VV-Sfus+ and challenged with an otherwise lethal dose of MHV-JHM before the induction of S-specific IgG antibodies. By contrast, a VV recombinant encoding a variant non fusogenic S-protein or the N-protein was not capable confering protection. In addition, we demonstrated that MHV-JHM S-specific IgG antibodies elicited before MHV-JHM challenge modulated the disease process, changing it from an acute disease to subacute demyelinating encephalomyelitis (SDE)." @default.
- W29563716 created "2016-06-24" @default.
- W29563716 creator A5003243065 @default.
- W29563716 creator A5039980888 @default.
- W29563716 creator A5046979947 @default.
- W29563716 creator A5076176227 @default.
- W29563716 date "1994-01-01" @default.
- W29563716 modified "2023-09-26" @default.
- W29563716 title "Recombinant Vaccinia Viruses Which Express MHV-JHM Proteins: Protective Immune Response and the Influence of Vaccination on Coronavirus-Induced Encephalomyelitis" @default.
- W29563716 cites W1409028342 @default.
- W29563716 cites W1514436302 @default.
- W29563716 cites W1547943245 @default.
- W29563716 cites W1548755772 @default.
- W29563716 cites W1599476759 @default.
- W29563716 cites W1971357443 @default.
- W29563716 cites W1983158097 @default.
- W29563716 cites W2021081800 @default.
- W29563716 cites W2022942097 @default.
- W29563716 cites W2044744307 @default.
- W29563716 cites W2045337210 @default.
- W29563716 cites W2053189269 @default.
- W29563716 cites W2069792166 @default.
- W29563716 cites W2070868863 @default.
- W29563716 cites W2103671635 @default.
- W29563716 cites W2115570300 @default.
- W29563716 cites W2152921605 @default.
- W29563716 cites W2172096973 @default.
- W29563716 doi "https://doi.org/10.1007/978-1-4615-2996-5_63" @default.
- W29563716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8209761" @default.
- W29563716 hasPublicationYear "1994" @default.
- W29563716 type Work @default.
- W29563716 sameAs 29563716 @default.
- W29563716 citedByCount "1" @default.
- W29563716 crossrefType "book-chapter" @default.
- W29563716 hasAuthorship W29563716A5003243065 @default.
- W29563716 hasAuthorship W29563716A5039980888 @default.
- W29563716 hasAuthorship W29563716A5046979947 @default.
- W29563716 hasAuthorship W29563716A5076176227 @default.
- W29563716 hasBestOaLocation W295637161 @default.
- W29563716 hasConcept C104317684 @default.
- W29563716 hasConcept C142724271 @default.
- W29563716 hasConcept C147483822 @default.
- W29563716 hasConcept C159047783 @default.
- W29563716 hasConcept C159654299 @default.
- W29563716 hasConcept C203014093 @default.
- W29563716 hasConcept C22070199 @default.
- W29563716 hasConcept C2522874641 @default.
- W29563716 hasConcept C2777648638 @default.
- W29563716 hasConcept C2777899865 @default.
- W29563716 hasConcept C2779134260 @default.
- W29563716 hasConcept C2780640218 @default.
- W29563716 hasConcept C2781356689 @default.
- W29563716 hasConcept C3008058167 @default.
- W29563716 hasConcept C40767141 @default.
- W29563716 hasConcept C524204448 @default.
- W29563716 hasConcept C54355233 @default.
- W29563716 hasConcept C71924100 @default.
- W29563716 hasConcept C86803240 @default.
- W29563716 hasConcept C8891405 @default.
- W29563716 hasConceptScore W29563716C104317684 @default.
- W29563716 hasConceptScore W29563716C142724271 @default.
- W29563716 hasConceptScore W29563716C147483822 @default.
- W29563716 hasConceptScore W29563716C159047783 @default.
- W29563716 hasConceptScore W29563716C159654299 @default.
- W29563716 hasConceptScore W29563716C203014093 @default.
- W29563716 hasConceptScore W29563716C22070199 @default.
- W29563716 hasConceptScore W29563716C2522874641 @default.
- W29563716 hasConceptScore W29563716C2777648638 @default.
- W29563716 hasConceptScore W29563716C2777899865 @default.
- W29563716 hasConceptScore W29563716C2779134260 @default.
- W29563716 hasConceptScore W29563716C2780640218 @default.
- W29563716 hasConceptScore W29563716C2781356689 @default.
- W29563716 hasConceptScore W29563716C3008058167 @default.
- W29563716 hasConceptScore W29563716C40767141 @default.
- W29563716 hasConceptScore W29563716C524204448 @default.
- W29563716 hasConceptScore W29563716C54355233 @default.
- W29563716 hasConceptScore W29563716C71924100 @default.
- W29563716 hasConceptScore W29563716C86803240 @default.
- W29563716 hasConceptScore W29563716C8891405 @default.
- W29563716 hasLocation W295637161 @default.
- W29563716 hasLocation W295637162 @default.
- W29563716 hasOpenAccess W29563716 @default.
- W29563716 hasPrimaryLocation W295637161 @default.
- W29563716 hasRelatedWork W1990427809 @default.
- W29563716 hasRelatedWork W2016551366 @default.
- W29563716 hasRelatedWork W2023089872 @default.
- W29563716 hasRelatedWork W2039932125 @default.
- W29563716 hasRelatedWork W2064248292 @default.
- W29563716 hasRelatedWork W2080039093 @default.
- W29563716 hasRelatedWork W2105219938 @default.
- W29563716 hasRelatedWork W2369427790 @default.
- W29563716 hasRelatedWork W2407030612 @default.
- W29563716 hasRelatedWork W2534183921 @default.
- W29563716 isParatext "false" @default.
- W29563716 isRetracted "false" @default.
- W29563716 magId "29563716" @default.
- W29563716 workType "book-chapter" @default.