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- W295645237 abstract "This chapter discusses the regulation of DNA replication and variegation-type position effects. An investigation of the replication patterns among chromosomes of Chinese hamster cells in culture indicated that the late replicating DNA was not a special class of chromosomal DNA. The evolution of special organelles for the control of replication is indicated by the currently known replication patterns, by condensation patterns, and by the spreading effects or gradients of inactivation in V-type position effects. The gradient in replication from the ends of the chromosome arms toward the centromeres, which was observed in Crepis, would be consistent with such a model with special organelles adjacent to centromeres or telomeres. Gradients in replication also occur in other chromosomes. The gradients in condensation observed in some prophase chromosomes may be another visible manifestation of the phenomenon." @default.
- W295645237 created "2016-06-24" @default.
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- W295645237 date "1964-01-01" @default.
- W295645237 modified "2023-10-16" @default.
- W295645237 title "REGULATION OF DNA REPLICATION AND VARIEGATION-TYPE POSITION EFFECTS11Work supported, in part, by Contract AT(30-1) 1304 with the U. S. Atomic Energy Commission." @default.
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- W295645237 doi "https://doi.org/10.1016/b978-1-4832-3076-4.50018-x" @default.
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