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- W2956853313 abstract "Clinical Chemistry is the backbone of medical treatment, diagnostics, and prevention. The laborato-ries are trying to improve the quality and to reduce diagnostic errors and processing time and safeguard trace-ability of all laboratory procedures to ensure patient safety. Six sigma belongs to statistical quality control and provides a new methodology for measuring and improving process performance in laboratory.Activities of AST, ALT, CK, LDH, Amy, and γ-GT were determined by standard kinetic methods on a Vitros 5600 biochemistry analyzer. Two daily quality controls (Verifier I and Verifier II) were run over 60 days. Total percent CV was calculated from routine daily QC. Between-instrument bias was also calculated from daily QC.The calculated sigma metrics for AST were 6.9 and 3.8; for ALT 9.3 and 5.6; for CK 6.6 and 5.3; LDH 5.2 and 5.2; for γ-GT 4.9 and 2.7; and for amylase 8.7 and 7.1. Analytical performance for AST, ALT, CK, LDH, and Amylase is world class. On the other hand, γ-GT analytical performance is poor.Six Sigma benefits from earlier quality management approaches that creates new challenges for medical laboratories." @default.
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- W2956853313 date "2019-01-01" @default.
- W2956853313 modified "2023-10-16" @default.
- W2956853313 title "Determination of Six Sigma Metric in Control of Enzymes Determination in Human Serum" @default.
- W2956853313 doi "https://doi.org/10.7754/clin.lab.2019.190108" @default.
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