Matches in SemOpenAlex for { <https://semopenalex.org/work/W2956987489> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2956987489 endingPage "369" @default.
- W2956987489 startingPage "369" @default.
- W2956987489 abstract "Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common type of autoimmune encephalitis. This study aimed to explore the possible factors affecting the response to first-line treatments in patients with anti-NMDAR encephalitis.We enrolled 29 patients who were diagnosed as anti-NMDAR encephalitis between January 1, 2015, and June 30, 2018. They were divided into the remission and nonremission groups according to their response to first-line treatments. The demographics, clinical manifestations, main ancillary examinations, follow-up treatments, and prognosis of patients were recorded. The symptoms reported on in this study occurred before treatments or during the course of first-line treatments.There were 18 patients (62.07%) in the remission group and 11 patients (37.93%) in the nonremission group. Compared to the remission group, a higher proportion of the patients in the nonremission group exhibited involuntary movements, decreased consciousness, central hypoventilation, lung infection, and hypoalbuminemia. The nonremission group had a high incidence of increased intracranial pressure and significant elevations of the neutrophil-to-lymphocyte ratio in peripheral blood (NLR), aspartate aminotransferase, and fibrinogen. Six patients (54.55%) in the nonremission group received second-line immunotherapy. Only one patient (3.45%) died, which was due to multiple-organ failure.Anti-NMDAR-encephalitis patients with more symptoms-especially involuntary movements, disturbance of consciousness, central hypoventilation, and accompanying hypoalbuminemia and pulmonary infection-may respond poorly to first-line treatments. Positive second-line immunotherapy therefore needs to be considered. Admission to an intensive-care unit, increased cerebrospinal fluid pressure, and increased NLR might be the significant factors affecting the response to first-line treatments." @default.
- W2956987489 created "2019-07-23" @default.
- W2956987489 creator A5019207894 @default.
- W2956987489 creator A5021783212 @default.
- W2956987489 creator A5023676457 @default.
- W2956987489 creator A5032750379 @default.
- W2956987489 creator A5042247903 @default.
- W2956987489 creator A5051424697 @default.
- W2956987489 date "2019-01-01" @default.
- W2956987489 modified "2023-10-14" @default.
- W2956987489 title "Factors Affecting the Response to First-Line Treatments in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis" @default.
- W2956987489 cites W1603573791 @default.
- W2956987489 cites W2030913782 @default.
- W2956987489 cites W2051552021 @default.
- W2956987489 cites W2070162113 @default.
- W2956987489 cites W2071570575 @default.
- W2956987489 cites W2098001563 @default.
- W2956987489 cites W2114398221 @default.
- W2956987489 cites W2163022996 @default.
- W2956987489 cites W2280783985 @default.
- W2956987489 cites W2335974062 @default.
- W2956987489 cites W2498432382 @default.
- W2956987489 cites W2519451855 @default.
- W2956987489 cites W2567266914 @default.
- W2956987489 cites W2567341982 @default.
- W2956987489 cites W2586640967 @default.
- W2956987489 cites W2745224986 @default.
- W2956987489 cites W2745764093 @default.
- W2956987489 cites W2755319088 @default.
- W2956987489 cites W2762938823 @default.
- W2956987489 cites W2782733419 @default.
- W2956987489 cites W2783109678 @default.
- W2956987489 cites W2797472478 @default.
- W2956987489 cites W2888347704 @default.
- W2956987489 cites W2898539043 @default.
- W2956987489 cites W2902040840 @default.
- W2956987489 cites W2906013886 @default.
- W2956987489 doi "https://doi.org/10.3988/jcn.2019.15.3.369" @default.
- W2956987489 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6620446" @default.
- W2956987489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31286710" @default.
- W2956987489 hasPublicationYear "2019" @default.
- W2956987489 type Work @default.
- W2956987489 sameAs 2956987489 @default.
- W2956987489 citedByCount "15" @default.
- W2956987489 countsByYear W29569874892020 @default.
- W2956987489 countsByYear W29569874892021 @default.
- W2956987489 countsByYear W29569874892022 @default.
- W2956987489 countsByYear W29569874892023 @default.
- W2956987489 crossrefType "journal-article" @default.
- W2956987489 hasAuthorship W2956987489A5019207894 @default.
- W2956987489 hasAuthorship W2956987489A5021783212 @default.
- W2956987489 hasAuthorship W2956987489A5023676457 @default.
- W2956987489 hasAuthorship W2956987489A5032750379 @default.
- W2956987489 hasAuthorship W2956987489A5042247903 @default.
- W2956987489 hasAuthorship W2956987489A5051424697 @default.
- W2956987489 hasBestOaLocation W29569874891 @default.
- W2956987489 hasConcept C126322002 @default.
- W2956987489 hasConcept C203014093 @default.
- W2956987489 hasConcept C2522874641 @default.
- W2956987489 hasConcept C2776009029 @default.
- W2956987489 hasConcept C71924100 @default.
- W2956987489 hasConcept C83455156 @default.
- W2956987489 hasConcept C90924648 @default.
- W2956987489 hasConceptScore W2956987489C126322002 @default.
- W2956987489 hasConceptScore W2956987489C203014093 @default.
- W2956987489 hasConceptScore W2956987489C2522874641 @default.
- W2956987489 hasConceptScore W2956987489C2776009029 @default.
- W2956987489 hasConceptScore W2956987489C71924100 @default.
- W2956987489 hasConceptScore W2956987489C83455156 @default.
- W2956987489 hasConceptScore W2956987489C90924648 @default.
- W2956987489 hasFunder F4320321001 @default.
- W2956987489 hasIssue "3" @default.
- W2956987489 hasLocation W29569874891 @default.
- W2956987489 hasLocation W29569874892 @default.
- W2956987489 hasLocation W29569874893 @default.
- W2956987489 hasLocation W29569874894 @default.
- W2956987489 hasOpenAccess W2956987489 @default.
- W2956987489 hasPrimaryLocation W29569874891 @default.
- W2956987489 hasRelatedWork W135870998 @default.
- W2956987489 hasRelatedWork W2111864547 @default.
- W2956987489 hasRelatedWork W2128595847 @default.
- W2956987489 hasRelatedWork W2316758749 @default.
- W2956987489 hasRelatedWork W2364357936 @default.
- W2956987489 hasRelatedWork W2591518573 @default.
- W2956987489 hasRelatedWork W2748952813 @default.
- W2956987489 hasRelatedWork W2899084033 @default.
- W2956987489 hasRelatedWork W3209926337 @default.
- W2956987489 hasRelatedWork W4307835419 @default.
- W2956987489 hasVolume "15" @default.
- W2956987489 isParatext "false" @default.
- W2956987489 isRetracted "false" @default.
- W2956987489 magId "2956987489" @default.
- W2956987489 workType "article" @default.