Matches in SemOpenAlex for { <https://semopenalex.org/work/W2958126902> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2958126902 endingPage "806" @default.
- W2958126902 startingPage "803" @default.
- W2958126902 abstract "Clitocybin A, isolated from the culture broth of mushroom Clitocybe aurantiaca, showed various biological activities such as cell death inhibition effects, anti‐wrinkle effects, aortic smooth muscle cell proliferation inhibition effects. In an effort to further develop this promising compound toward a potent antioxidant, we have modified the structure of clitocybin A by changing the number of free phenolic hydrogen in isoindolinone moiety. In this paper, clitocybin A and its analogues, clitocybin B and C were synthesized and their antioxidant activities were evaluated. Clitocybin A possessing two phenolic hydrogens in isoindolinone moiety of clitocybin A analogues showed more potent radical scavenging activity than clitocybin B possessing one phenolic hydrogen. In inhibition of cellular DNA damage in H2O2treated cells, clitocybin C lacking free phenolic hydrogen in isoindolinone moiety showed more potent activity than clitocybin A possessing two phenolic hydrogens.Among the tested compounds, clitocybin A only showed dose‐dependently HNE inhibitory activity with an IC50 value of 78.8 uM. The presence of free phenolic hydrogens inisoindolinone moiety of clitocybin A analogues plays an important role in antioxidant activities." @default.
- W2958126902 created "2019-07-23" @default.
- W2958126902 creator A5007130453 @default.
- W2958126902 creator A5009566312 @default.
- W2958126902 creator A5013507111 @default.
- W2958126902 creator A5014739246 @default.
- W2958126902 creator A5071260315 @default.
- W2958126902 date "2019-07-07" @default.
- W2958126902 modified "2023-10-16" @default.
- W2958126902 title "Synthesis of Clitocybin A, B and C and their Biological Evaluation for Antioxidant Activities" @default.
- W2958126902 cites W1565388169 @default.
- W2958126902 cites W1968679020 @default.
- W2958126902 cites W1970181728 @default.
- W2958126902 cites W2004947881 @default.
- W2958126902 cites W2012991711 @default.
- W2958126902 cites W2018778205 @default.
- W2958126902 cites W2024931990 @default.
- W2958126902 cites W2031596649 @default.
- W2958126902 cites W2044442756 @default.
- W2958126902 cites W2044641122 @default.
- W2958126902 cites W2053840721 @default.
- W2958126902 cites W2054841332 @default.
- W2958126902 cites W2057251121 @default.
- W2958126902 cites W2105141970 @default.
- W2958126902 cites W2107238743 @default.
- W2958126902 cites W2174614343 @default.
- W2958126902 cites W2617135261 @default.
- W2958126902 cites W4233735523 @default.
- W2958126902 cites W4377248427 @default.
- W2958126902 doi "https://doi.org/10.1002/bkcs.11825" @default.
- W2958126902 hasPublicationYear "2019" @default.
- W2958126902 type Work @default.
- W2958126902 sameAs 2958126902 @default.
- W2958126902 citedByCount "1" @default.
- W2958126902 countsByYear W29581269022023 @default.
- W2958126902 crossrefType "journal-article" @default.
- W2958126902 hasAuthorship W2958126902A5007130453 @default.
- W2958126902 hasAuthorship W2958126902A5009566312 @default.
- W2958126902 hasAuthorship W2958126902A5013507111 @default.
- W2958126902 hasAuthorship W2958126902A5014739246 @default.
- W2958126902 hasAuthorship W2958126902A5071260315 @default.
- W2958126902 hasConcept C116073593 @default.
- W2958126902 hasConcept C185592680 @default.
- W2958126902 hasConcept C202751555 @default.
- W2958126902 hasConcept C21951064 @default.
- W2958126902 hasConcept C2776568683 @default.
- W2958126902 hasConcept C2777752497 @default.
- W2958126902 hasConcept C2778004101 @default.
- W2958126902 hasConcept C55493867 @default.
- W2958126902 hasConcept C71240020 @default.
- W2958126902 hasConceptScore W2958126902C116073593 @default.
- W2958126902 hasConceptScore W2958126902C185592680 @default.
- W2958126902 hasConceptScore W2958126902C202751555 @default.
- W2958126902 hasConceptScore W2958126902C21951064 @default.
- W2958126902 hasConceptScore W2958126902C2776568683 @default.
- W2958126902 hasConceptScore W2958126902C2777752497 @default.
- W2958126902 hasConceptScore W2958126902C2778004101 @default.
- W2958126902 hasConceptScore W2958126902C55493867 @default.
- W2958126902 hasConceptScore W2958126902C71240020 @default.
- W2958126902 hasIssue "8" @default.
- W2958126902 hasLocation W29581269021 @default.
- W2958126902 hasOpenAccess W2958126902 @default.
- W2958126902 hasPrimaryLocation W29581269021 @default.
- W2958126902 hasRelatedWork W1973397307 @default.
- W2958126902 hasRelatedWork W2000546257 @default.
- W2958126902 hasRelatedWork W2002433690 @default.
- W2958126902 hasRelatedWork W2041228289 @default.
- W2958126902 hasRelatedWork W2057931667 @default.
- W2958126902 hasRelatedWork W2067184525 @default.
- W2958126902 hasRelatedWork W2169595296 @default.
- W2958126902 hasRelatedWork W2486576046 @default.
- W2958126902 hasRelatedWork W2727445327 @default.
- W2958126902 hasRelatedWork W2952540846 @default.
- W2958126902 hasVolume "40" @default.
- W2958126902 isParatext "false" @default.
- W2958126902 isRetracted "false" @default.
- W2958126902 magId "2958126902" @default.
- W2958126902 workType "article" @default.