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- W2958320278 abstract "Abstract Objective : To compare the sensitivity of the ThinPrep test by self-collected vaginal tampon for cervical cytology in women with abnormal Pap smears and their pathological diagnosis Design : Diagnostic test Setting/population : Eighty-one women with abnormal results of Pap smear within the previous 6 months were recruited from the colposcopy clinic of Department of Obstetrics and Gynaecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand from September 2009 to May 2010. Methods : Participants inserted a vaginal tampon on the morning and removed it before a colposcopic examination on the afternoon. Vaginal tampons were then immersed into a vial of ThinPrep Presrv-Cyt solution and sent to a cytopathologist for analysis. Results were compared to the final pathological diagnosis. Outcome measures : Outcomes of the ThinPrep test by self-collected vaginal tampon detecting any abnormalities (ASC-US, ASC-H, LSIL, HSIL, SCC, AGC, AGC-FN, AIS, Adenocarcinoma) compared to final pathological diagnosis. Results : The ThinPrep test with self-collected vaginal tampon detected abnormalities with the sensitivity of 35.1%, specificity of 87.5%, PPV of 86.9% and NPV of 36.2%. The sensitivity of our ThinPrep test to specifically diagnose CIN 3 was 50% when compared to the final pathological diagnosis. The adequacy of specimens for diagnosis with our ThinPrep test was 67%. Conclusions: The ThinPrep test obtained by self-collected vaginal tampon was an alternative method for detection of abnormal cytology in women with abnormal Pap smear. Further studying of this technique as a follow-up method for women with abnormal cervical pathology after colposcopy evaluation would be interesting. Keywords : Cervical cancer, conventional Pap smear, cytology, self- collected vaginal tampon, ThinPrep" @default.
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- W2958320278 date "2019-05-08" @default.
- W2958320278 modified "2023-09-27" @default.
- W2958320278 title "Sensitivity of ThinPrep Test by Self-collected Vaginal Tampon in Women with Abnormal Pap Smear" @default.
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