FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2958394019> ?p ?o ?g. }

• W2958394019 endingPage "216" @default.
• W2958394019 startingPage "209" @default.
• W2958394019 abstract "Abstract Aim We previously reported that methamphetamine (METH)‐induced conditioned place preference was attenuated by Shati/Nat8l overexpression in the medial prefrontal cortex (mPFC). Shati/Nat8l overexpression in the mPFC expressed lower levels of both glutamate and dopamine (DA) in the nucleus accumbens (NAc) and attenuated METH‐induced DA elevation. We suggested a mechanism in which a decline of glutamate levels in the NAc decreases extracellular DA levels. However, the hypothesis has not confirmed. Methods We conducted a recovery experiments by pre‐microinjection of an mGluR group II antagonist, LY341495, into the NAc shell of mPFC‐Shati/Nat8l‐overexpressed mice followed by METH injection and DA levels measurement by in vivo microdialysis. Results Pretreatment with LY341495 was able to restore METH‐induced DA increase. Furthermore, mice injected with an adeno‐associated virus vector containing GFP (AAV‐GFP vector) in the mPFC expressed a colocalization of GFP with DARPP‐32 a medium spiny neuron (MSN) marker. Next, co‐immunostaining of DARPP‐32 and neuronal nitric oxide synthase (nNOS: expressed in a subtype of gamma‐Aminobutyric acid (GABA interneurons) in ventral tegmental area (VTA) showed a colocalization of nNOS and DARPP‐32. Conclusion These results provided a proof that Shati/Nat8l attenuation of METH‐induced DA increase is mediated by mGluR group II in the NAc. Moreover, immunohistochemical study showed a direct connection of mPFC projection neurons with NAc MSN and a connection of MSN projection neurons with a subtype of GABA interneurons in VTA." @default.
• W2958394019 created "2019-07-23" @default.
• W2958394019 creator A5012827429 @default.
• W2958394019 creator A5017145635 @default.
• W2958394019 creator A5017641271 @default.
• W2958394019 creator A5060591351 @default.
• W2958394019 creator A5089879313 @default.
• W2958394019 date "2019-07-08" @default.
• W2958394019 modified "2023-10-01" @default.
• W2958394019 title "Regulatory system of mGluR group II in the nucleus accumbens for methamphetamine‐induced dopamine increase by the medial prefrontal cortex" @default.
• W2958394019 cites W1600525795 @default.
• W2958394019 cites W1651595496 @default.
• W2958394019 cites W1965246238 @default.
• W2958394019 cites W1974366641 @default.
• W2958394019 cites W1983779076 @default.
• W2958394019 cites W1997503854 @default.
• W2958394019 cites W2004160530 @default.
• W2958394019 cites W2012949542 @default.
• W2958394019 cites W2016029955 @default.
• W2958394019 cites W2019041433 @default.
• W2958394019 cites W2026098772 @default.
• W2958394019 cites W2037385027 @default.
• W2958394019 cites W2048358667 @default.
• W2958394019 cites W2050416880 @default.
• W2958394019 cites W2051609565 @default.
• W2958394019 cites W2055212957 @default.
• W2958394019 cites W2056214647 @default.
• W2958394019 cites W2065601975 @default.
• W2958394019 cites W2073595900 @default.
• W2958394019 cites W2088602317 @default.
• W2958394019 cites W2095349960 @default.
• W2958394019 cites W2104438363 @default.
• W2958394019 cites W2106305205 @default.
• W2958394019 cites W2106719141 @default.
• W2958394019 cites W2112824246 @default.
• W2958394019 cites W2113381203 @default.
• W2958394019 cites W2115414869 @default.
• W2958394019 cites W2119641401 @default.
• W2958394019 cites W2122956388 @default.
• W2958394019 cites W2134330719 @default.
• W2958394019 cites W2138718114 @default.
• W2958394019 cites W2145257920 @default.
• W2958394019 cites W2149178067 @default.
• W2958394019 cites W2166436976 @default.
• W2958394019 cites W2184692915 @default.
• W2958394019 cites W2277185635 @default.
• W2958394019 cites W2761837776 @default.
• W2958394019 cites W2782249154 @default.
• W2958394019 cites W2926410262 @default.
• W2958394019 cites W2952733232 @default.
• W2958394019 cites W2958394019 @default.
• W2958394019 cites W4322696256 @default.
• W2958394019 doi "https://doi.org/10.1002/npr2.12068" @default.
• W2958394019 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7292294" @default.
• W2958394019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31283871" @default.
• W2958394019 hasPublicationYear "2019" @default.
• W2958394019 type Work @default.
• W2958394019 sameAs 2958394019 @default.
• W2958394019 citedByCount "7" @default.
• W2958394019 countsByYear W29583940192019 @default.
• W2958394019 countsByYear W29583940192020 @default.
• W2958394019 countsByYear W29583940192021 @default.
• W2958394019 crossrefType "journal-article" @default.
• W2958394019 hasAuthorship W2958394019A5012827429 @default.
• W2958394019 hasAuthorship W2958394019A5017145635 @default.
• W2958394019 hasAuthorship W2958394019A5017641271 @default.
• W2958394019 hasAuthorship W2958394019A5060591351 @default.
• W2958394019 hasAuthorship W2958394019A5089879313 @default.
• W2958394019 hasBestOaLocation W29583940191 @default.
• W2958394019 hasConcept C126322002 @default.
• W2958394019 hasConcept C137183658 @default.
• W2958394019 hasConcept C166940927 @default.
• W2958394019 hasConcept C169760540 @default.
• W2958394019 hasConcept C169900460 @default.
• W2958394019 hasConcept C170493617 @default.
• W2958394019 hasConcept C178790620 @default.
• W2958394019 hasConcept C185592680 @default.
• W2958394019 hasConcept C2776552330 @default.
• W2958394019 hasConcept C2779989194 @default.
• W2958394019 hasConcept C2780114369 @default.
• W2958394019 hasConcept C2780376393 @default.
• W2958394019 hasConcept C2780948874 @default.
• W2958394019 hasConcept C2781195155 @default.
• W2958394019 hasConcept C49051014 @default.
• W2958394019 hasConcept C50156730 @default.
• W2958394019 hasConcept C513476851 @default.
• W2958394019 hasConcept C521977710 @default.
• W2958394019 hasConcept C55493867 @default.
• W2958394019 hasConcept C61174792 @default.
• W2958394019 hasConcept C71924100 @default.
• W2958394019 hasConcept C86803240 @default.
• W2958394019 hasConcept C98274493 @default.
• W2958394019 hasConceptScore W2958394019C126322002 @default.
• W2958394019 hasConceptScore W2958394019C137183658 @default.
• W2958394019 hasConceptScore W2958394019C166940927 @default.
• W2958394019 hasConceptScore W2958394019C169760540 @default.
• W2958394019 hasConceptScore W2958394019C169900460 @default.
• W2958394019 hasConceptScore W2958394019C170493617 @default.

• next