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- W2958447767 abstract "Des données récentes neurobiologiques ont permis de montrer que tous les produits qui déclenchent une dépendance chez l’homme (amphétamine, cocaïne, morphine, héroïne, cannabis...) augmentent la libération de dopamine dans une structure sous-corticale, le noyau accumbens. Ce noyau fait partie d’un ensemble de structures cérébrales, dénommé « circuit de la récompense » qui définit à chaque instant l’état physique et psychique dans lequel se trouve l’individu. Les drogues, en modifiant la cinétique et l’amplitude de la production de dopamine, induisent une sensation de satisfaction. Cette dérégulation conduit le toxicomane à mémoriser artificiellement les événements associés à la prise de produit et à en devenir dépendant. Recent neurobiological data have indicated that almost all drugs of abuse (amphetamine, cocaine, morphine, heroin, cannabis...) increase dopamine release in a sub-cortical structure, the nucleus accumbens. This nucleus is part of different cerebral structures, named « reward system » which constantly defines physical and mental states of an individual. Development of addiction would be due to the modification, by drugs of abuse, of the kinetic and the amplitude of dopamine release. Such a dysregulation would induce the addict to artificially memorize any event linked to the product consumption." @default.
- W2958447767 created "2019-07-23" @default.
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- W2958447767 date "2002-02-01" @default.
- W2958447767 modified "2023-10-16" @default.
- W2958447767 title "La place de la dopamine dans les processus de dépendance aux drogues" @default.
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- W2958447767 doi "https://doi.org/10.1016/s0001-4079(19)34336-5" @default.
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