FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2958510721> ?p ?o ?g. }

• W2958510721 endingPage "1188" @default.
• W2958510721 startingPage "1183" @default.
• W2958510721 abstract "Background Budesonide has been proven to be an effective treatment for microscopic colitis (MC). However, the two current commercially available preparations are released in the ileum. Beclomethasone dipropionate (Clipper®) is a synthetic corticosteroid with topical colonic release. Objective This study aimed to explore whether an open‐label treatment with beclomethasone dipropionate is an effective treatment for MC. Methods Prospectively collected data of 30 patients from six centres were retrospectively analysed. All patients had a confirmed diagnosis of idiopathic MC (lymphocytic and collagenous colitis) and were symptomatic (i.e. ≥ 21 loose stools over a seven‐day period). Treatment consisted of 10 mg beclomethasone daily for four weeks, followed by 5 mg daily for another four weeks. The primary end point was the proportion of patients in remission (i.e. a mean of < 3 stools/day and a mean of <1 watery stool per day) after an eight‐week treatment period. Secondary end points were the proportion of patients responding to therapy at weeks 4 and 8, remission at weeks 4 and 12 and relapse at week 12. Reported adverse events were collected. Results Overall, at week 8, remission was achieved in 70%, and 77% of patients were responding to treatment. After four weeks of treatment, 80% were responding, and 67% were in remission. Four weeks after stopping treatment, 60% were still in remission. Conclusion This open‐label study suggests that an eight‐week course of beclomethasone could be a promising and relatively safe treatment for MC. A randomised controlled study is warranted." @default.
• W2958510721 created "2019-07-23" @default.
• W2958510721 creator A5002506154 @default.
• W2958510721 creator A5003730541 @default.
• W2958510721 creator A5004604080 @default.
• W2958510721 creator A5004718384 @default.
• W2958510721 creator A5007763883 @default.
• W2958510721 creator A5011762769 @default.
• W2958510721 creator A5022022076 @default.
• W2958510721 creator A5023142523 @default.
• W2958510721 creator A5028891384 @default.
• W2958510721 creator A5037568293 @default.
• W2958510721 creator A5068475926 @default.
• W2958510721 creator A5070357055 @default.
• W2958510721 creator A5077379335 @default.
• W2958510721 date "2019-11-01" @default.
• W2958510721 modified "2023-09-26" @default.
• W2958510721 title "Beclomethasone dipropionate in microscopic colitis: Results of an exploratory open‐label multicentre study (COLCO)" @default.
• W2958510721 cites W1968358910 @default.
• W2958510721 cites W1993342556 @default.
• W2958510721 cites W2018223454 @default.
• W2958510721 cites W2020299608 @default.
• W2958510721 cites W2033334628 @default.
• W2958510721 cites W2044883546 @default.
• W2958510721 cites W2054346643 @default.
• W2958510721 cites W2060038066 @default.
• W2958510721 cites W2061902236 @default.
• W2958510721 cites W2062440272 @default.
• W2958510721 cites W2072998439 @default.
• W2958510721 cites W2080694161 @default.
• W2958510721 cites W2115758598 @default.
• W2958510721 cites W2116836515 @default.
• W2958510721 cites W2133189168 @default.
• W2958510721 cites W2142934444 @default.
• W2958510721 cites W2145611254 @default.
• W2958510721 cites W2149148307 @default.
• W2958510721 cites W2156083031 @default.
• W2958510721 cites W2444653804 @default.
• W2958510721 cites W2599490571 @default.
• W2958510721 doi "https://doi.org/10.1177/2050640619860965" @default.
• W2958510721 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6826530" @default.
• W2958510721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31700631" @default.
• W2958510721 hasPublicationYear "2019" @default.
• W2958510721 type Work @default.
• W2958510721 sameAs 2958510721 @default.
• W2958510721 citedByCount "8" @default.
• W2958510721 countsByYear W29585107212019 @default.
• W2958510721 countsByYear W29585107212020 @default.
• W2958510721 countsByYear W29585107212021 @default.
• W2958510721 countsByYear W29585107212022 @default.
• W2958510721 crossrefType "journal-article" @default.
• W2958510721 hasAuthorship W2958510721A5002506154 @default.
• W2958510721 hasAuthorship W2958510721A5003730541 @default.
• W2958510721 hasAuthorship W2958510721A5004604080 @default.
• W2958510721 hasAuthorship W2958510721A5004718384 @default.
• W2958510721 hasAuthorship W2958510721A5007763883 @default.
• W2958510721 hasAuthorship W2958510721A5011762769 @default.
• W2958510721 hasAuthorship W2958510721A5022022076 @default.
• W2958510721 hasAuthorship W2958510721A5023142523 @default.
• W2958510721 hasAuthorship W2958510721A5028891384 @default.
• W2958510721 hasAuthorship W2958510721A5037568293 @default.
• W2958510721 hasAuthorship W2958510721A5068475926 @default.
• W2958510721 hasAuthorship W2958510721A5070357055 @default.
• W2958510721 hasAuthorship W2958510721A5077379335 @default.
• W2958510721 hasBestOaLocation W29585107211 @default.
• W2958510721 hasConcept C126322002 @default.
• W2958510721 hasConcept C141071460 @default.
• W2958510721 hasConcept C197934379 @default.
• W2958510721 hasConcept C2776136866 @default.
• W2958510721 hasConcept C2776804153 @default.
• W2958510721 hasConcept C2778260677 @default.
• W2958510721 hasConcept C2778561856 @default.
• W2958510721 hasConcept C2779134260 @default.
• W2958510721 hasConcept C3019800554 @default.
• W2958510721 hasConcept C71924100 @default.
• W2958510721 hasConcept C90924648 @default.
• W2958510721 hasConceptScore W2958510721C126322002 @default.
• W2958510721 hasConceptScore W2958510721C141071460 @default.
• W2958510721 hasConceptScore W2958510721C197934379 @default.
• W2958510721 hasConceptScore W2958510721C2776136866 @default.
• W2958510721 hasConceptScore W2958510721C2776804153 @default.
• W2958510721 hasConceptScore W2958510721C2778260677 @default.
• W2958510721 hasConceptScore W2958510721C2778561856 @default.
• W2958510721 hasConceptScore W2958510721C2779134260 @default.
• W2958510721 hasConceptScore W2958510721C3019800554 @default.
• W2958510721 hasConceptScore W2958510721C71924100 @default.
• W2958510721 hasConceptScore W2958510721C90924648 @default.
• W2958510721 hasIssue "9" @default.
• W2958510721 hasLocation W29585107211 @default.
• W2958510721 hasLocation W29585107212 @default.
• W2958510721 hasLocation W29585107213 @default.
• W2958510721 hasLocation W29585107214 @default.
• W2958510721 hasOpenAccess W2958510721 @default.
• W2958510721 hasPrimaryLocation W29585107211 @default.
• W2958510721 hasRelatedWork W1987680534 @default.
• W2958510721 hasRelatedWork W1991897564 @default.
• W2958510721 hasRelatedWork W2000658018 @default.
• W2958510721 hasRelatedWork W2006480451 @default.

• next