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- W2958679919 abstract "Migraine and cluster headache (CH) are complex disorders characterized by recurrent episodes of headache. Although the two are regarded as distinct primary headache disorders, the clinical boundaries between CH and migraine are sometimes poorly defined, and there can be considerable overlap between the characteristics of the two headache types. Given the inherent clinical variability in these two headache disorders, it is likely that some patients will exhibit overlapping symptoms of CH and migraine. Although the pathogenesis of these two headache disorders remains to be fully understood, accumulating evidence suggests important roles for the trigeminovascular system and release of sensory neuropeptides. Neuroimaging studies have suggested a potential role of the dorsolateral pons, hypothalamus, and trigeminal nucleus caudalis in generating migraine attacks, while the hypothalamus is firmly implicated in the pathophysiology of CH. Additionally, some treatments may be effective for both migraine and CH, further supporting the notion that their pathophysiology may overlap. In this chapter, we review the clinical and pathophysiological differences and similarities between migraine and CH, highlighting the need for further research regarding the mechanisms underlying such differences and similarities." @default.
- W2958679919 created "2019-07-23" @default.
- W2958679919 creator A5019480561 @default.
- W2958679919 creator A5028390017 @default.
- W2958679919 creator A5061626486 @default.
- W2958679919 date "2019-07-18" @default.
- W2958679919 modified "2023-09-27" @default.
- W2958679919 title "Migraine and Cluster Headache: Differences and Similarities" @default.
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