FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2959389076> ?p ?o ?g. }

• W2959389076 endingPage "869" @default.
• W2959389076 startingPage "857" @default.
• W2959389076 abstract "Medical nutrition therapy for long-chain fatty acid oxidation disorders (LC-FAODs) currently emphasizes fasting avoidance, restricted dietary long-chain fatty acid intake, supplementation with medium chain triglycerides, and increased carbohydrate intake. We hypothesize that increasing dietary protein intake relative to carbohydrate intake would preserve metabolic control yet induce physical benefits including reduced hepatic lipogenesis. Therefore, we compared two dietary approaches with similar fat intake but different carbohydrate to protein ratios in participants diagnosed with LC-FAODs. Thirteen participants were enrolled and randomized into either a high-protein (PRO) or a high-carbohydrate (CHO) diet for 4 months. Baseline and 4-month assessments included body composition, ectopic lipid deposition, and resting energy expenditure. End of study assessments also included total energy expenditure, metabolic responses to oral feedings, and whole-body fatty acid oxidation capacity. At the end of the dietary intervention, both groups had similar energy expenditure, fat and glucose oxidation rates, and glucolipid responses to mixed meal and oral glucose loads. Neither dietary group experienced worsening symptoms related to their LC-FAOD. Compared to the CHO group, the PRO group exhibited increased blood levels of short-chain acylcarnitines, reduced intrahepatic lipid content, and maintained lean body mass while the CHO group lost lean mass. In patients with LC-FAODs, increasing protein intake maintained metabolic control, reduced liver fat without risk of metabolic decompensation, and helped preserve lean body mass. We propose that a modest increase in dietary protein along with fasting avoidance and fat restriction may improve body composition and energy expenditure in patients with LC-FAODs." @default.
• W2959389076 created "2019-07-23" @default.
• W2959389076 creator A5000032345 @default.
• W2959389076 creator A5002194433 @default.
• W2959389076 creator A5017473577 @default.
• W2959389076 creator A5040468813 @default.
• W2959389076 creator A5054652468 @default.
• W2959389076 creator A5085602557 @default.
• W2959389076 creator A5086318125 @default.
• W2959389076 date "2019-07-24" @default.
• W2959389076 modified "2023-10-16" @default.
• W2959389076 title "Higher dietary protein intake preserves lean body mass, lowers liver lipid deposition, and maintains metabolic control in participants with long‐chain fatty acid oxidation disorders" @default.
• W2959389076 cites W1515849222 @default.
• W2959389076 cites W1574255071 @default.
• W2959389076 cites W1784651233 @default.
• W2959389076 cites W1895133111 @default.
• W2959389076 cites W1983168533 @default.
• W2959389076 cites W1983791877 @default.
• W2959389076 cites W2012377595 @default.
• W2959389076 cites W2055131908 @default.
• W2959389076 cites W2062274757 @default.
• W2959389076 cites W2078495381 @default.
• W2959389076 cites W2082537561 @default.
• W2959389076 cites W2087659442 @default.
• W2959389076 cites W2139260293 @default.
• W2959389076 cites W2157489298 @default.
• W2959389076 cites W2160539605 @default.
• W2959389076 cites W2161674805 @default.
• W2959389076 cites W2162657548 @default.
• W2959389076 cites W2163974964 @default.
• W2959389076 cites W2165340329 @default.
• W2959389076 cites W2167851640 @default.
• W2959389076 cites W2169325452 @default.
• W2959389076 cites W2169607998 @default.
• W2959389076 cites W2171392078 @default.
• W2959389076 cites W2283087284 @default.
• W2959389076 cites W2467390086 @default.
• W2959389076 cites W2623402661 @default.
• W2959389076 cites W2751445216 @default.
• W2959389076 cites W2885965240 @default.
• W2959389076 cites W31397147 @default.
• W2959389076 doi "https://doi.org/10.1002/jimd.12155" @default.
• W2959389076 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7452215" @default.
• W2959389076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31295363" @default.
• W2959389076 hasPublicationYear "2019" @default.
• W2959389076 type Work @default.
• W2959389076 sameAs 2959389076 @default.
• W2959389076 citedByCount "6" @default.
• W2959389076 countsByYear W29593890762020 @default.
• W2959389076 countsByYear W29593890762021 @default.
• W2959389076 countsByYear W29593890762022 @default.
• W2959389076 countsByYear W29593890762023 @default.
• W2959389076 crossrefType "journal-article" @default.
• W2959389076 hasAuthorship W2959389076A5000032345 @default.
• W2959389076 hasAuthorship W2959389076A5002194433 @default.
• W2959389076 hasAuthorship W2959389076A5017473577 @default.
• W2959389076 hasAuthorship W2959389076A5040468813 @default.
• W2959389076 hasAuthorship W2959389076A5054652468 @default.
• W2959389076 hasAuthorship W2959389076A5085602557 @default.
• W2959389076 hasAuthorship W2959389076A5086318125 @default.
• W2959389076 hasBestOaLocation W29593890762 @default.
• W2959389076 hasConcept C120863210 @default.
• W2959389076 hasConcept C126322002 @default.
• W2959389076 hasConcept C134018914 @default.
• W2959389076 hasConcept C147583825 @default.
• W2959389076 hasConcept C185592680 @default.
• W2959389076 hasConcept C2778772119 @default.
• W2959389076 hasConcept C2779134260 @default.
• W2959389076 hasConcept C2780578515 @default.
• W2959389076 hasConcept C2993503589 @default.
• W2959389076 hasConcept C31903555 @default.
• W2959389076 hasConcept C511355011 @default.
• W2959389076 hasConcept C543025807 @default.
• W2959389076 hasConcept C55493867 @default.
• W2959389076 hasConcept C71924100 @default.
• W2959389076 hasConcept C82714985 @default.
• W2959389076 hasConcept C86803240 @default.
• W2959389076 hasConceptScore W2959389076C120863210 @default.
• W2959389076 hasConceptScore W2959389076C126322002 @default.
• W2959389076 hasConceptScore W2959389076C134018914 @default.
• W2959389076 hasConceptScore W2959389076C147583825 @default.
• W2959389076 hasConceptScore W2959389076C185592680 @default.
• W2959389076 hasConceptScore W2959389076C2778772119 @default.
• W2959389076 hasConceptScore W2959389076C2779134260 @default.
• W2959389076 hasConceptScore W2959389076C2780578515 @default.
• W2959389076 hasConceptScore W2959389076C2993503589 @default.
• W2959389076 hasConceptScore W2959389076C31903555 @default.
• W2959389076 hasConceptScore W2959389076C511355011 @default.
• W2959389076 hasConceptScore W2959389076C543025807 @default.
• W2959389076 hasConceptScore W2959389076C55493867 @default.
• W2959389076 hasConceptScore W2959389076C71924100 @default.
• W2959389076 hasConceptScore W2959389076C82714985 @default.
• W2959389076 hasConceptScore W2959389076C86803240 @default.
• W2959389076 hasFunder F4320332161 @default.
• W2959389076 hasIssue "5" @default.
• W2959389076 hasLocation W29593890761 @default.
• W2959389076 hasLocation W29593890762 @default.
• W2959389076 hasOpenAccess W2959389076 @default.

• next