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- W2959598675 abstract "Significance The optic tectum (the superior colliculus in mammals) is central for visuomotor transformation in all vertebrates. Here, we investigate the mechanisms underlying the selection between approaching and evasive movements. We use an isolated eye–brain–spinal cord preparation from the lamprey that allows us to display different types of visual stimuli (e.g., looming stimuli) and, at the same time, record neural activity from specific brain regions and the behavioral output monitored through the ventral roots. We show that 2 classes of brainstem-projecting neurons in the deep layer of tectum, in interaction with local inhibitory interneurons, are responsible for the selective switch between visually triggered approaching or evasive movements. We suggest that these visual decision-making circuits are phylogenetically conserved throughout vertebrate evolution." @default.
- W2959598675 created "2019-07-23" @default.
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- W2959598675 date "2019-07-11" @default.
- W2959598675 modified "2023-10-06" @default.
- W2959598675 title "The role of the optic tectum for visually evoked orienting and evasive movements" @default.
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- W2959598675 doi "https://doi.org/10.1073/pnas.1907962116" @default.
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