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- W2959671168 abstract "Molecular probes have become an important tool to decipher cell and molecular events, as well as contributing to clinical diagnosis. In this study, we report on a novel bioluminescence affiprobe and evaluate its functionality by monitoring HER2 expression in the prostate cancer cells. The proposed bioluminescence affiprobe consists of a binding domain, an HER2 specific affibody molecule and a bioluminescent domain, recombinant Renilla luciferase. The experiments indicate that bioluminescence affiprobe can serve as a reliable and user-friendly probe for the detection of human HER2 positive prostate cells as well as ex vivo based detection of HER2-positive human prostate cancer specimens using luminometeric-based assays." @default.
- W2959671168 created "2019-07-23" @default.
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- W2959671168 date "2019-10-01" @default.
- W2959671168 modified "2023-10-18" @default.
- W2959671168 title "Detection of a prostate cancer cell line using a bioluminescent affiprobe: An attempt to develop a new molecular probe for ex vivo studies" @default.
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- W2959671168 doi "https://doi.org/10.1016/j.ijbiomac.2019.07.085" @default.
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