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- W2960147366 abstract "The aim of this study is to evaluate the association between urinary megalin, renal function, blood pressure, lipid profile, vitamin D and glycemic control in patients with type 2 diabetes mellitus (T2DM).. This was a cross-sectional study which recruited 209 patients with T2DM. Urinary megalin was positively associated with systolic blood pressure (SBP) (r=0.218, p=0.04) but negatively with glomerular filtration rate (GFR) (r=-0.16, p=0.023). The levels of urinary albumin, triglycerides (TGs) and glycosylated hemoglobin (HbA1c) were higher in the high-megalin group, compared to those in low-megalin group. Moreover, there was a significant inverse association between vitamin D3 levels and megalin levels in urine (OR=0.281, p=0.047).Our study showed for the first time that megalin is associated with progression factors of diabetic nephropathy as well as vitamin D deficiency (Tab. 3, Fig. 1, Ref. 15)." @default.
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- W2960147366 date "2019-01-01" @default.
- W2960147366 modified "2023-09-25" @default.
- W2960147366 title "Urinary megalin in association with progression factors of diabetic nephropathy" @default.
- W2960147366 doi "https://doi.org/10.4149/bll_2019_086" @default.
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