FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2960463668> ?p ?o ?g. }

• W2960463668 endingPage "120142" @default.
• W2960463668 startingPage "120142" @default.
• W2960463668 abstract "We reported here two novel electrochemical impedance spectroscopy biosensors were developed for the first time for highly sensitive quantification of matrix metalloproteinase-14 (MMP-14) based on binding interaction between hemopexin-like domain (PEX) of MMP-14 (PEX-14) and its inhibitory peptides. Specific inhibitory peptides (IVSC or ISC) inhibiting homodimerization or heterodimerization of MMP-14 was first self assembled on the surface of gold electrode and blocked with 6-mercapto-1-hexanol on a gold electrode surface used as IVSC or ISC modified biosensor, respectively. IVSC modified biosensor can be used for detection of MMP-14 by using the direct IVSC-MMP-14 interaction inhibiting MMP-14 homodimerization as well as ISC modified biosensor for indirect detection of MMP-14 via PEX-14 mediated peptide-MMP-14 binding. The electron transfer resistance (Ret) of biosensor was monitored to measure MMP-14 using Fe(CN)63−/4- as probe. The increase of the Ret of the biosensors are linear with the concentration of MMP-14 in the range from 1 μg L−1 to 10 μg L−1 with detection limit of 0.19 μg L−1 for IVSC modified biosensor and 0.1 ng L−1 to 50 ng L−1 with detection limit of 7 ng L−1 for ISC modified biosensor. This work demonstrates that probing the interaction between peptide inhibitor and PEX of MMPs represents a novel approach to assess MMPs-mediated cancer dissemination." @default.
• W2960463668 created "2019-07-23" @default.
• W2960463668 creator A5044098681 @default.
• W2960463668 creator A5052676364 @default.
• W2960463668 creator A5055004640 @default.
• W2960463668 creator A5073144121 @default.
• W2960463668 date "2019-12-01" @default.
• W2960463668 modified "2023-09-30" @default.
• W2960463668 title "Electrochemical impedance spectroscopy for quantization of matrix Metalloproteinase-14 based on peptides inhibiting its homodimerization and heterodimerization" @default.
• W2960463668 cites W1977652757 @default.
• W2960463668 cites W1980638845 @default.
• W2960463668 cites W1990651316 @default.
• W2960463668 cites W1999502956 @default.
• W2960463668 cites W2004260843 @default.
• W2960463668 cites W2006764470 @default.
• W2960463668 cites W2007066284 @default.
• W2960463668 cites W2010004352 @default.
• W2960463668 cites W2010254599 @default.
• W2960463668 cites W2026893670 @default.
• W2960463668 cites W2041764146 @default.
• W2960463668 cites W2043521546 @default.
• W2960463668 cites W2055758035 @default.
• W2960463668 cites W2060605943 @default.
• W2960463668 cites W2064991281 @default.
• W2960463668 cites W2069776459 @default.
• W2960463668 cites W2079570021 @default.
• W2960463668 cites W2083979957 @default.
• W2960463668 cites W2084569284 @default.
• W2960463668 cites W2089682022 @default.
• W2960463668 cites W2093403489 @default.
• W2960463668 cites W2098803628 @default.
• W2960463668 cites W2102144787 @default.
• W2960463668 cites W2103868159 @default.
• W2960463668 cites W2158081780 @default.
• W2960463668 cites W2334455532 @default.
• W2960463668 cites W2401707519 @default.
• W2960463668 cites W2604313283 @default.
• W2960463668 cites W2614658780 @default.
• W2960463668 cites W2738795682 @default.
• W2960463668 cites W2765547738 @default.
• W2960463668 cites W2770088450 @default.
• W2960463668 cites W2896563492 @default.
• W2960463668 doi "https://doi.org/10.1016/j.talanta.2019.120142" @default.
• W2960463668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31450394" @default.
• W2960463668 hasPublicationYear "2019" @default.
• W2960463668 type Work @default.
• W2960463668 sameAs 2960463668 @default.
• W2960463668 citedByCount "9" @default.
• W2960463668 countsByYear W29604636682019 @default.
• W2960463668 countsByYear W29604636682020 @default.
• W2960463668 countsByYear W29604636682021 @default.
• W2960463668 countsByYear W29604636682022 @default.
• W2960463668 countsByYear W29604636682023 @default.
• W2960463668 crossrefType "journal-article" @default.
• W2960463668 hasAuthorship W2960463668A5044098681 @default.
• W2960463668 hasAuthorship W2960463668A5052676364 @default.
• W2960463668 hasAuthorship W2960463668A5055004640 @default.
• W2960463668 hasAuthorship W2960463668A5073144121 @default.
• W2960463668 hasConcept C109523444 @default.
• W2960463668 hasConcept C119128265 @default.
• W2960463668 hasConcept C12554922 @default.
• W2960463668 hasConcept C131649739 @default.
• W2960463668 hasConcept C147789679 @default.
• W2960463668 hasConcept C160756335 @default.
• W2960463668 hasConcept C17525397 @default.
• W2960463668 hasConcept C185592680 @default.
• W2960463668 hasConcept C21951064 @default.
• W2960463668 hasConcept C2779281246 @default.
• W2960463668 hasConcept C43617362 @default.
• W2960463668 hasConcept C52859227 @default.
• W2960463668 hasConcept C55493867 @default.
• W2960463668 hasConcept C7040849 @default.
• W2960463668 hasConcept C7070889 @default.
• W2960463668 hasConcept C86803240 @default.
• W2960463668 hasConceptScore W2960463668C109523444 @default.
• W2960463668 hasConceptScore W2960463668C119128265 @default.
• W2960463668 hasConceptScore W2960463668C12554922 @default.
• W2960463668 hasConceptScore W2960463668C131649739 @default.
• W2960463668 hasConceptScore W2960463668C147789679 @default.
• W2960463668 hasConceptScore W2960463668C160756335 @default.
• W2960463668 hasConceptScore W2960463668C17525397 @default.
• W2960463668 hasConceptScore W2960463668C185592680 @default.
• W2960463668 hasConceptScore W2960463668C21951064 @default.
• W2960463668 hasConceptScore W2960463668C2779281246 @default.
• W2960463668 hasConceptScore W2960463668C43617362 @default.
• W2960463668 hasConceptScore W2960463668C52859227 @default.
• W2960463668 hasConceptScore W2960463668C55493867 @default.
• W2960463668 hasConceptScore W2960463668C7040849 @default.
• W2960463668 hasConceptScore W2960463668C7070889 @default.
• W2960463668 hasConceptScore W2960463668C86803240 @default.
• W2960463668 hasFunder F4320324173 @default.
• W2960463668 hasFunder F4320335983 @default.
• W2960463668 hasLocation W29604636681 @default.
• W2960463668 hasLocation W29604636682 @default.
• W2960463668 hasOpenAccess W2960463668 @default.
• W2960463668 hasPrimaryLocation W29604636681 @default.
• W2960463668 hasRelatedWork W1969760125 @default.
• W2960463668 hasRelatedWork W1990083472 @default.

• next