FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2960484691> ?p ?o ?g. }

• W2960484691 abstract "Seasonal thermal remodelling (acclimatization) and laboratory thermal remodelling (acclimation) can induce different physiological changes in ectothermic animals. As global temperatures are changing at an increasing rate, there is urgency to understand the compensatory abilities of key organs like the heart to adjust under natural conditions. Thus, the aim of the present study was to directly compare the acclimatization and acclimatory response within a single eurythermal fish species, the European shorthorn sculpin (Myoxocephalus scorpio L.). We used current- and voltage-clamp to measure ionic current densities in both isolated atrial and ventricular myocytes at a common temperature of 7.5°C from three groups of fish: 1) summer-acclimated (SumAcl, 12°C); 2) cold-acclimated (ColdAcl, 3°C); and 3) winter-acclimatized fish (WinAcz, 3°C). At the common test temperature of 7.5°C, action potential (AP) was shortened by both WinAcz and ColdAcl, compared with SumAcl, however, WinAcz caused a greater shortening than did ColdAcl. Shortening of AP was achieved mostly by a significant increase in repolarizing current density (IKr and IK1) following WinAcz, with ColdAcl having only minor effects. Compared with SumAcl, the depolarizing L-type calcium current (ICa) was larger following WinAcz, but again there was no effect of ColdAcl on ICa. Interestingly, the other depolarizing current, INa was downregulated at low temperatures. Our analysis further shows that ionic current remodelling is primarily due to changes ion channel density rather than currents kinetics. In summary, acclimatization profoundly modified the electrical activity of the sculpin heart while acclimation to the same temperature for &gt;1.5 month produced very limited remodelling effects." @default.
• W2960484691 created "2019-07-23" @default.
• W2960484691 creator A5007538992 @default.
• W2960484691 creator A5052713266 @default.
• W2960484691 creator A5074400045 @default.
• W2960484691 date "2019-01-01" @default.
• W2960484691 modified "2023-10-16" @default.
• W2960484691 title "Thermal acclimation and seasonal acclimatization: a comparative study of cardiac response to prolonged temperature change in shorthorn sculpin" @default.
• W2960484691 cites W1768540043 @default.
• W2960484691 cites W1955316225 @default.
• W2960484691 cites W1972066237 @default.
• W2960484691 cites W1972898520 @default.
• W2960484691 cites W1977114675 @default.
• W2960484691 cites W1978419749 @default.
• W2960484691 cites W1978983583 @default.
• W2960484691 cites W1986847977 @default.
• W2960484691 cites W1987564766 @default.
• W2960484691 cites W1995097643 @default.
• W2960484691 cites W1997254505 @default.
• W2960484691 cites W1998090234 @default.
• W2960484691 cites W1998293680 @default.
• W2960484691 cites W2000577735 @default.
• W2960484691 cites W2007763367 @default.
• W2960484691 cites W2013783859 @default.
• W2960484691 cites W2019719304 @default.
• W2960484691 cites W2026032512 @default.
• W2960484691 cites W2029255645 @default.
• W2960484691 cites W2029827068 @default.
• W2960484691 cites W2031227814 @default.
• W2960484691 cites W2034424425 @default.
• W2960484691 cites W2042961461 @default.
• W2960484691 cites W2045812059 @default.
• W2960484691 cites W2052109950 @default.
• W2960484691 cites W2054497994 @default.
• W2960484691 cites W2054651001 @default.
• W2960484691 cites W2058376978 @default.
• W2960484691 cites W2076344992 @default.
• W2960484691 cites W2078829960 @default.
• W2960484691 cites W2080386316 @default.
• W2960484691 cites W2093388433 @default.
• W2960484691 cites W2094103799 @default.
• W2960484691 cites W2095235425 @default.
• W2960484691 cites W2097377307 @default.
• W2960484691 cites W2097614706 @default.
• W2960484691 cites W2105839968 @default.
• W2960484691 cites W2107370819 @default.
• W2960484691 cites W2108472299 @default.
• W2960484691 cites W2109009509 @default.
• W2960484691 cites W2111568589 @default.
• W2960484691 cites W2122337429 @default.
• W2960484691 cites W2125505135 @default.
• W2960484691 cites W2127934972 @default.
• W2960484691 cites W2133743353 @default.
• W2960484691 cites W2133895266 @default.
• W2960484691 cites W2133930356 @default.
• W2960484691 cites W2134136120 @default.
• W2960484691 cites W2134236543 @default.
• W2960484691 cites W2136683838 @default.
• W2960484691 cites W2142350140 @default.
• W2960484691 cites W2147045269 @default.
• W2960484691 cites W2148725662 @default.
• W2960484691 cites W2149253160 @default.
• W2960484691 cites W2150754564 @default.
• W2960484691 cites W2152302095 @default.
• W2960484691 cites W2152949957 @default.
• W2960484691 cites W2164223435 @default.
• W2960484691 cites W2170492770 @default.
• W2960484691 cites W2171167586 @default.
• W2960484691 cites W2171719931 @default.
• W2960484691 cites W2214202090 @default.
• W2960484691 cites W2215857688 @default.
• W2960484691 cites W2256069935 @default.
• W2960484691 cites W2283463510 @default.
• W2960484691 cites W2287537455 @default.
• W2960484691 cites W2413209645 @default.
• W2960484691 cites W2526494718 @default.
• W2960484691 cites W2555487521 @default.
• W2960484691 cites W2561038073 @default.
• W2960484691 cites W2586025285 @default.
• W2960484691 cites W2611823004 @default.
• W2960484691 cites W2791771398 @default.
• W2960484691 cites W2914811651 @default.
• W2960484691 cites W4249476632 @default.
• W2960484691 doi "https://doi.org/10.1242/jeb.202242" @default.
• W2960484691 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31315933" @default.
• W2960484691 hasPublicationYear "2019" @default.
• W2960484691 type Work @default.
• W2960484691 sameAs 2960484691 @default.
• W2960484691 citedByCount "13" @default.
• W2960484691 countsByYear W29604846912019 @default.
• W2960484691 countsByYear W29604846912020 @default.
• W2960484691 countsByYear W29604846912021 @default.
• W2960484691 countsByYear W29604846912022 @default.
• W2960484691 countsByYear W29604846912023 @default.
• W2960484691 crossrefType "journal-article" @default.
• W2960484691 hasAuthorship W2960484691A5007538992 @default.
• W2960484691 hasAuthorship W2960484691A5052713266 @default.
• W2960484691 hasAuthorship W2960484691A5074400045 @default.
• W2960484691 hasBestOaLocation W29604846911 @default.
• W2960484691 hasConcept C119406331 @default.

• next