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• W296089738 abstract "Multiple sclerosis (MS) is a progressive disease that predominantly affects young adults. Patients typically experience one-sided weakness, sensory problems, visual disturbances, double vision, and/or pain. The disease initially develops in spurts (attacks) during which symptoms are worsened, separated by periods of remission that can last many months with nearly complete resolution of symptoms. Over time, remissions become incomplete and symptoms worsen progressively. Women are three times more likely to develop MS than men and MS is more common in Caucasians than in Asians or Africans. The cause of MS is not known, but an autoimmune response to the myelin insulation of nerve cells is strongly suspected. Multiple lesions containing lymphocytes and macrophages are found throughout the brain and spinal cord where nerve cells are damaged and signaling compromised. The development of lesions can be followed using magnetic resonance imaging, but number and size of lesions do not predict disease severity. Treatment is symptomatic, but recent disease-modifying drugs that attenuate the body's immune response delay disease progression in many patients. Death from MS is rare and life expectancy almost normal, but quality of life gradually deteriorates." @default.
• W296089738 created "2016-06-24" @default.
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• W296089738 date "2015-01-01" @default.
• W296089738 modified "2023-09-27" @default.
• W296089738 title "Multiple Sclerosis" @default.
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• W296089738 doi "https://doi.org/10.1016/b978-0-12-800244-5.00008-2" @default.
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