Matches in SemOpenAlex for { <https://semopenalex.org/work/W2960964771> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2960964771 endingPage "1829" @default.
- W2960964771 startingPage "1825" @default.
- W2960964771 abstract "Starting from the respective tertiary α-silylmethyl amines, the intramolecular cyclization of α-aminoalkyl radicals to Michael acceptors produced tetrahydroisoquinolines. The reaction conditions included the use of 5 mol% of an iridium photoredox catalyst, dimethylformamide as the solvent, and equimolar amounts of water and cesium carbonate as the additives. 13 substrates were synthesized from ortho-alkylbenzaldehydes in a three-step procedure involving a carbonyl condensation, a radical bromination, and a substitution by a secondary α-silylmethyl amine. After optimization of the photocyclization, the reaction delivered tetrahydroisoquinolines in moderate to high yields (41–83%). A facial diastereoselectivity (dr ≅ 80:20) was observed with chiral substrates and a crystal structure provided evidence for the relative configuration of the major diastereoisomer. A catalytic cycle with direct electron transfer to the photoexcited metal catalyst is proposed." @default.
- W2960964771 created "2019-07-23" @default.
- W2960964771 creator A5025015822 @default.
- W2960964771 creator A5052374956 @default.
- W2960964771 creator A5078484982 @default.
- W2960964771 date "2019-07-17" @default.
- W2960964771 modified "2023-09-27" @default.
- W2960964771 title "Synthesis of Tetrahydroisoquinolines by Visible-Light-Mediated 6-exo-trig Cyclization of α-Aminoalkyl Radicals" @default.
- W2960964771 cites W1970393749 @default.
- W2960964771 cites W1974797953 @default.
- W2960964771 cites W1999031172 @default.
- W2960964771 cites W2012615651 @default.
- W2960964771 cites W2014807637 @default.
- W2960964771 cites W2043566098 @default.
- W2960964771 cites W2051419557 @default.
- W2960964771 cites W2059156553 @default.
- W2960964771 cites W2094129737 @default.
- W2960964771 cites W2138771200 @default.
- W2960964771 cites W2518726767 @default.
- W2960964771 cites W2532587842 @default.
- W2960964771 cites W2913204808 @default.
- W2960964771 cites W2951806183 @default.
- W2960964771 doi "https://doi.org/10.1055/s-0039-1690006" @default.
- W2960964771 hasPublicationYear "2019" @default.
- W2960964771 type Work @default.
- W2960964771 sameAs 2960964771 @default.
- W2960964771 citedByCount "4" @default.
- W2960964771 countsByYear W29609647712020 @default.
- W2960964771 countsByYear W29609647712021 @default.
- W2960964771 crossrefType "journal-article" @default.
- W2960964771 hasAuthorship W2960964771A5025015822 @default.
- W2960964771 hasAuthorship W2960964771A5052374956 @default.
- W2960964771 hasAuthorship W2960964771A5078484982 @default.
- W2960964771 hasConcept C131779359 @default.
- W2960964771 hasConcept C138716334 @default.
- W2960964771 hasConcept C139066938 @default.
- W2960964771 hasConcept C155647269 @default.
- W2960964771 hasConcept C161790260 @default.
- W2960964771 hasConcept C178790620 @default.
- W2960964771 hasConcept C185592680 @default.
- W2960964771 hasConcept C2776406546 @default.
- W2960964771 hasConcept C2777712214 @default.
- W2960964771 hasConcept C2780471494 @default.
- W2960964771 hasConcept C63338738 @default.
- W2960964771 hasConcept C65973085 @default.
- W2960964771 hasConcept C75079739 @default.
- W2960964771 hasConcept C75473681 @default.
- W2960964771 hasConceptScore W2960964771C131779359 @default.
- W2960964771 hasConceptScore W2960964771C138716334 @default.
- W2960964771 hasConceptScore W2960964771C139066938 @default.
- W2960964771 hasConceptScore W2960964771C155647269 @default.
- W2960964771 hasConceptScore W2960964771C161790260 @default.
- W2960964771 hasConceptScore W2960964771C178790620 @default.
- W2960964771 hasConceptScore W2960964771C185592680 @default.
- W2960964771 hasConceptScore W2960964771C2776406546 @default.
- W2960964771 hasConceptScore W2960964771C2777712214 @default.
- W2960964771 hasConceptScore W2960964771C2780471494 @default.
- W2960964771 hasConceptScore W2960964771C63338738 @default.
- W2960964771 hasConceptScore W2960964771C65973085 @default.
- W2960964771 hasConceptScore W2960964771C75079739 @default.
- W2960964771 hasConceptScore W2960964771C75473681 @default.
- W2960964771 hasIssue "15" @default.
- W2960964771 hasLocation W29609647711 @default.
- W2960964771 hasOpenAccess W2960964771 @default.
- W2960964771 hasPrimaryLocation W29609647711 @default.
- W2960964771 hasRelatedWork W1979583681 @default.
- W2960964771 hasRelatedWork W1983223629 @default.
- W2960964771 hasRelatedWork W2019571757 @default.
- W2960964771 hasRelatedWork W2075761790 @default.
- W2960964771 hasRelatedWork W2086439248 @default.
- W2960964771 hasRelatedWork W254406356 @default.
- W2960964771 hasRelatedWork W2952171652 @default.
- W2960964771 hasRelatedWork W2952938583 @default.
- W2960964771 hasRelatedWork W93455268 @default.
- W2960964771 hasRelatedWork W2015310757 @default.
- W2960964771 hasVolume "30" @default.
- W2960964771 isParatext "false" @default.
- W2960964771 isRetracted "false" @default.
- W2960964771 magId "2960964771" @default.
- W2960964771 workType "article" @default.