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• W2961253218 abstract "Introduction of axial chirality in bioactive 3-indolyl furanoids has been achieved by systematic alteration of functional groups around the stereogenic axis, keeping in mind that atropisomerically pure analogues may possess different binding affinities and selectivities towards a target protein. The kinetics of racemization of axially chiral 3-indolyl furanoids have been studied through chiral HPLC analysis, electronic circular dichroism (ECD) spectroscopy, and computational modeling. The results identify the configurational parameters for optically pure 3-indolyl furanoids to exist as stable and isolable atropisomeric form." @default.
• W2961253218 created "2019-07-23" @default.
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• W2961253218 date "2019-01-01" @default.
• W2961253218 modified "2023-09-23" @default.
• W2961253218 title "Establishment of atropisomerism in 3-indolyl furanoids: a synthetic, experimental and theoretical perspective" @default.
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• W2961253218 doi "https://doi.org/10.1039/c9ra05350f" @default.
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• W2961253218 hasPublicationYear "2019" @default.
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