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- W2961358405 endingPage "279" @default.
- W2961358405 startingPage "279" @default.
- W2961358405 abstract "The bacterial flagellum is a helical filamentous organelle responsible for motility. In bacterial species possessing flagella at the cell exterior, the long helical flagellar filament acts as a molecular screw to generate thrust. Meanwhile, the flagella of spirochetes reside within the periplasmic space and not only act as a cytoskeleton to determine the helicity of the cell body, but also rotate or undulate the helical cell body for propulsion. Despite structural diversity of the flagella among bacterial species, flagellated bacteria share a common rotary nanomachine, namely the flagellar motor, which is located at the base of the filament. The flagellar motor is composed of a rotor ring complex and multiple transmembrane stator units and converts the ion flux through an ion channel of each stator unit into the mechanical work required for motor rotation. Intracellular chemotactic signaling pathways regulate the direction of flagella-driven motility in response to changes in the environments, allowing bacteria to migrate towards more desirable environments for their survival. Recent experimental and theoretical studies have been deepening our understanding of the molecular mechanisms of the flagellar motor. In this review article, we describe the current understanding of the structure and dynamics of the bacterial flagellum." @default.
- W2961358405 created "2019-07-23" @default.
- W2961358405 creator A5078668392 @default.
- W2961358405 creator A5088842005 @default.
- W2961358405 date "2019-07-14" @default.
- W2961358405 modified "2023-10-10" @default.
- W2961358405 title "Flagella-Driven Motility of Bacteria" @default.
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