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• W2962489063 abstract "Abstract Introduction The prognostic significance of P‐wave morphology in patients with coronary artery disease (CAD) is not well‐known. Methods A total of 1946 patients with angiographically verified CAD were included in the Innovation to reduce Cardiovascular Complications of Diabetes at the Intersection (ARTEMIS) study. The P‐wave morphology could be analyzed in 1797 patients. Results During 7.4 ± 2.0 years, a total of 168 (9.3%) patients died or experienced resuscitation from sudden cardiac arrest (SCA), 43 (2.4%) patients experienced sudden cardiac death (SCD) or were resuscitated from SCA, 37 (2.1%) patients succumbed to non‐SCD (NSCD), and 88 (4.9%) patients to noncardiac death (NCD). Of the P‐wave parameters, the absolute P‐wave residuum (PWR), the heterogeneity of the P‐wave morphology (PWH), and the P‐wave duration (Pdur) had the closest univariate association with the risk of SCD/SCA (0.0038 ± 0.0026 vs 0.0022 ± 0.0017, P < .001; 11.0 ± 5.2 vs 8.6 ± 3.6, P < .01; 142.7 ± 16.9 vs 134.8 ± 14.3 milliseconds, P < .01; SCD/SCA vs no SCD/SCA, respectively). After adjustments with factors that were associated with the risk of SCD/SCA, such as diabetes, smoking, left bundle branch block, high‐sensitivity C‐reactive protein, and high‐sensitivity troponin T, PWR ( P < .001), PWH ( P < .05), and Pdur ( P < 0.01) still predicted SCD/SCA but not non‐sudden cardiac death. When these parameters were added to the SCD/SCA clinical risk model, the discrimination and reclassification accuracy of the risk model increased significantly ( P < .05, P < .001) and the C‐index increased from 0.745 to 0.787. Conclusion The P‐wave morphology parameters independently predict SCD/SCA in patients with CAD." @default.
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• W2962489063 date "2019-07-25" @default.
• W2962489063 modified "2023-09-27" @default.
• W2962489063 title "Prognostic significance of P‐wave morphology in patients with coronary artery disease" @default.
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• W2962489063 doi "https://doi.org/10.1111/jce.14066" @default.
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