Matches in SemOpenAlex for { <https://semopenalex.org/work/W2962730219> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2962730219 abstract "Cancer prognosis and treatment efficacy are assessed by evaluating the hallmarks of a tumor which are volume change of the tumor and the vascular network reformation around a tumor. Non-invasive quantitative assessment of those indications, in-vivo, is still a challenge for traditional imaging modalities, owing to a large interrogation area and deep-seated molecular (fluorescence) signal in highly scattering, anatomically complex skin tissue. Currently available techniques either utilize surgically implanted imaging windows or conduct terminal experiments for each time point. The former is prone to inflammation at the implantation site thus interfering with the tumor microenvironment. The latter one is prone to sample variability thus results in a pseudo-longitudinal outcome for tumor development. Here, we combine Intravital Fluorescence Tomography (IFT) and Spectral Domain Optical Coherence Tomography (SD-OCT) for tumor imaging with a Non-invasive Intravital Imaging Window (NIIW) for tissue stabilization. This platform enabled us to follow tumor development non-invasively covering tumor initiation, development and regression on the same animal over months-long period. IFT-OCT multimodal imaging not only reveals tumor volume change but also skin anatomical features, and it is capable of revealing neo-vascularization around the tumor site. This platform thus serves as a useful noninvasive tool to explore future research questions pertaining to cancer biology in common fluorescence-based mouse models, such as tumor progression or treatment efficacy. In addition, our multi-modal platform alleviates the burden put on animals while imaging and reduce the experimental cost significantly." @default.
- W2962730219 created "2019-07-30" @default.
- W2962730219 creator A5005479893 @default.
- W2962730219 creator A5006081452 @default.
- W2962730219 creator A5050487837 @default.
- W2962730219 creator A5064104261 @default.
- W2962730219 creator A5080244060 @default.
- W2962730219 creator A5089540670 @default.
- W2962730219 date "2019-07-19" @default.
- W2962730219 modified "2023-09-26" @default.
- W2962730219 title "Longitudinal monitoring of in-vivo mice mammary tumor progression using intravital fluorescence tomography and optical coherence tomography" @default.
- W2962730219 cites W2066031699 @default.
- W2962730219 cites W2109994415 @default.
- W2962730219 cites W2156754943 @default.
- W2962730219 cites W2398214726 @default.
- W2962730219 cites W2594149640 @default.
- W2962730219 cites W2613512560 @default.
- W2962730219 cites W2767602287 @default.
- W2962730219 doi "https://doi.org/10.1117/12.2527035" @default.
- W2962730219 hasPublicationYear "2019" @default.
- W2962730219 type Work @default.
- W2962730219 sameAs 2962730219 @default.
- W2962730219 citedByCount "0" @default.
- W2962730219 crossrefType "proceedings-article" @default.
- W2962730219 hasAuthorship W2962730219A5005479893 @default.
- W2962730219 hasAuthorship W2962730219A5006081452 @default.
- W2962730219 hasAuthorship W2962730219A5050487837 @default.
- W2962730219 hasAuthorship W2962730219A5064104261 @default.
- W2962730219 hasAuthorship W2962730219A5080244060 @default.
- W2962730219 hasAuthorship W2962730219A5089540670 @default.
- W2962730219 hasConcept C121332964 @default.
- W2962730219 hasConcept C121608353 @default.
- W2962730219 hasConcept C126322002 @default.
- W2962730219 hasConcept C126838900 @default.
- W2962730219 hasConcept C12722491 @default.
- W2962730219 hasConcept C136229726 @default.
- W2962730219 hasConcept C142724271 @default.
- W2962730219 hasConcept C150903083 @default.
- W2962730219 hasConcept C207001950 @default.
- W2962730219 hasConcept C2778818243 @default.
- W2962730219 hasConcept C2779256057 @default.
- W2962730219 hasConcept C2859252 @default.
- W2962730219 hasConcept C29331040 @default.
- W2962730219 hasConcept C57477423 @default.
- W2962730219 hasConcept C62520636 @default.
- W2962730219 hasConcept C71924100 @default.
- W2962730219 hasConcept C86803240 @default.
- W2962730219 hasConcept C91881484 @default.
- W2962730219 hasConceptScore W2962730219C121332964 @default.
- W2962730219 hasConceptScore W2962730219C121608353 @default.
- W2962730219 hasConceptScore W2962730219C126322002 @default.
- W2962730219 hasConceptScore W2962730219C126838900 @default.
- W2962730219 hasConceptScore W2962730219C12722491 @default.
- W2962730219 hasConceptScore W2962730219C136229726 @default.
- W2962730219 hasConceptScore W2962730219C142724271 @default.
- W2962730219 hasConceptScore W2962730219C150903083 @default.
- W2962730219 hasConceptScore W2962730219C207001950 @default.
- W2962730219 hasConceptScore W2962730219C2778818243 @default.
- W2962730219 hasConceptScore W2962730219C2779256057 @default.
- W2962730219 hasConceptScore W2962730219C2859252 @default.
- W2962730219 hasConceptScore W2962730219C29331040 @default.
- W2962730219 hasConceptScore W2962730219C57477423 @default.
- W2962730219 hasConceptScore W2962730219C62520636 @default.
- W2962730219 hasConceptScore W2962730219C71924100 @default.
- W2962730219 hasConceptScore W2962730219C86803240 @default.
- W2962730219 hasConceptScore W2962730219C91881484 @default.
- W2962730219 hasLocation W29627302191 @default.
- W2962730219 hasOpenAccess W2962730219 @default.
- W2962730219 hasPrimaryLocation W29627302191 @default.
- W2962730219 hasRelatedWork W1980768570 @default.
- W2962730219 hasRelatedWork W2042876152 @default.
- W2962730219 hasRelatedWork W2055057719 @default.
- W2962730219 hasRelatedWork W2057904358 @default.
- W2962730219 hasRelatedWork W2064831387 @default.
- W2962730219 hasRelatedWork W2115655191 @default.
- W2962730219 hasRelatedWork W2116742093 @default.
- W2962730219 hasRelatedWork W2122976856 @default.
- W2962730219 hasRelatedWork W2152138693 @default.
- W2962730219 hasRelatedWork W2344429631 @default.
- W2962730219 hasRelatedWork W2517445332 @default.
- W2962730219 hasRelatedWork W2550896371 @default.
- W2962730219 hasRelatedWork W2555614964 @default.
- W2962730219 hasRelatedWork W2756390436 @default.
- W2962730219 hasRelatedWork W2901672945 @default.
- W2962730219 hasRelatedWork W2989876673 @default.
- W2962730219 hasRelatedWork W3040643881 @default.
- W2962730219 hasRelatedWork W3042130693 @default.
- W2962730219 hasRelatedWork W3130530302 @default.
- W2962730219 hasRelatedWork W3147026690 @default.
- W2962730219 isParatext "false" @default.
- W2962730219 isRetracted "false" @default.
- W2962730219 magId "2962730219" @default.
- W2962730219 workType "article" @default.