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• W2962777341 abstract "Circovirus is the smallest virus known to replicate autonomously. Knowledge of viral genome release may provide understanding of viral replication and a method to artificially inactivate viral particles. Currently, little is known about the release model of porcine circovirus type 2 (PCV2). Here, we report the release of the PCV2 genome from assembled capsid and the intracellular trafficking of infectious PCV2 by alterations in the capsid conformation. Knowledge of PCV2 capsid stability and dynamics is essential to understanding its infectious cycle and lays the foundation for discovering powerful targets for therapeutic and prophylactic intervention." @default.
• W2962777341 created "2019-07-30" @default.
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• W2962777341 date "2019-10-15" @default.
• W2962777341 modified "2023-09-28" @default.
• W2962777341 title "Conformational Changes and Nuclear Entry of Porcine Circovirus without Disassembly" @default.
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• W2962777341 doi "https://doi.org/10.1128/jvi.00824-19" @default.
• W2962777341 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6798103" @default.
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