Matches in SemOpenAlex for { <https://semopenalex.org/work/W2962837550> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2962837550 endingPage "49" @default.
- W2962837550 startingPage "49" @default.
- W2962837550 abstract "Several studies have previously reported propolis, or its constituents, to inhibit tumour angiogenesis 1 . The anti-angiogenic activity of two Indonesian stingless bee propolis extracts from Sulawesi Island on vascular cells were assessed. Sample D01 was obtained from the outer side of bee hives, while D02 was from the inner side of the same hives. Preliminary results of cell viability and multi-channel wound healing assays o n HUVECs and placenta-derived pericytes demonstrated that D01 elicited a strong cytotoxic effect and a considerable anti-migratory activity on the vascular cells. Although D02 demonstrated a much weaker cytotoxic effect on the cell lines compared to D01, it elicited a substantial protective effect on the pericytes against CoCl 2 -induced dropout in an experiment to mimic a micro - environment commonly associated with angiogenesis and tumour growth 2 . These results demonstrate modulatory effects of these propolis samples in vascular cells, which requires further investigation . The extracts were profiled by using liquid chromatography coupled to high resolution mass spectrometry . The most abundant compounds in Indonesian sample D 0 1 from LC-MS analysis seem to be unusual since they do not immediately fall into a clear class such as flavonoids or terpenoids. Two of the most abundant compound s have elemental compositions matching actinopyrones which are antibiotic compounds isolated from Streptomyces pactum 3 . Identification on the basis of elemental composition is not definitive but compounds in D 0 1 are possibly due to unusually modified terpenoids. Sample D 0 2 has abundant compounds which include four related diterpenes with differing degrees of oxygenation and some sesquiterpenes. However, again the profile is unusual." @default.
- W2962837550 created "2019-07-30" @default.
- W2962837550 creator A5006929320 @default.
- W2962837550 creator A5027767420 @default.
- W2962837550 creator A5044325531 @default.
- W2962837550 creator A5069174970 @default.
- W2962837550 creator A5076176731 @default.
- W2962837550 date "2018-12-08" @default.
- W2962837550 modified "2023-09-26" @default.
- W2962837550 title "Preliminary Studies: The Potential Anti-Angiogenic Activities of Two Sulavesi Island (Indonesia) Propolis and Their Chemical Characterization" @default.
- W2962837550 hasPublicationYear "2018" @default.
- W2962837550 type Work @default.
- W2962837550 sameAs 2962837550 @default.
- W2962837550 citedByCount "0" @default.
- W2962837550 crossrefType "journal-article" @default.
- W2962837550 hasAuthorship W2962837550A5006929320 @default.
- W2962837550 hasAuthorship W2962837550A5027767420 @default.
- W2962837550 hasAuthorship W2962837550A5044325531 @default.
- W2962837550 hasAuthorship W2962837550A5069174970 @default.
- W2962837550 hasAuthorship W2962837550A5076176731 @default.
- W2962837550 hasConcept C154317977 @default.
- W2962837550 hasConcept C181674461 @default.
- W2962837550 hasConcept C185592680 @default.
- W2962837550 hasConcept C202751555 @default.
- W2962837550 hasConcept C206103511 @default.
- W2962837550 hasConcept C2779732960 @default.
- W2962837550 hasConcept C2780394083 @default.
- W2962837550 hasConcept C2780488879 @default.
- W2962837550 hasConcept C2781438746 @default.
- W2962837550 hasConcept C502942594 @default.
- W2962837550 hasConcept C55493867 @default.
- W2962837550 hasConcept C556039675 @default.
- W2962837550 hasConcept C59822182 @default.
- W2962837550 hasConcept C71924100 @default.
- W2962837550 hasConcept C86803240 @default.
- W2962837550 hasConceptScore W2962837550C154317977 @default.
- W2962837550 hasConceptScore W2962837550C181674461 @default.
- W2962837550 hasConceptScore W2962837550C185592680 @default.
- W2962837550 hasConceptScore W2962837550C202751555 @default.
- W2962837550 hasConceptScore W2962837550C206103511 @default.
- W2962837550 hasConceptScore W2962837550C2779732960 @default.
- W2962837550 hasConceptScore W2962837550C2780394083 @default.
- W2962837550 hasConceptScore W2962837550C2780488879 @default.
- W2962837550 hasConceptScore W2962837550C2781438746 @default.
- W2962837550 hasConceptScore W2962837550C502942594 @default.
- W2962837550 hasConceptScore W2962837550C55493867 @default.
- W2962837550 hasConceptScore W2962837550C556039675 @default.
- W2962837550 hasConceptScore W2962837550C59822182 @default.
- W2962837550 hasConceptScore W2962837550C71924100 @default.
- W2962837550 hasConceptScore W2962837550C86803240 @default.
- W2962837550 hasIssue "3" @default.
- W2962837550 hasLocation W29628375501 @default.
- W2962837550 hasOpenAccess W2962837550 @default.
- W2962837550 hasPrimaryLocation W29628375501 @default.
- W2962837550 hasRelatedWork W1999894985 @default.
- W2962837550 hasRelatedWork W2071699141 @default.
- W2962837550 hasRelatedWork W2417216584 @default.
- W2962837550 hasRelatedWork W2742442342 @default.
- W2962837550 hasRelatedWork W2744260951 @default.
- W2962837550 hasRelatedWork W2767789966 @default.
- W2962837550 hasRelatedWork W2903204625 @default.
- W2962837550 hasRelatedWork W2943800267 @default.
- W2962837550 hasRelatedWork W2962691109 @default.
- W2962837550 hasRelatedWork W2963241369 @default.
- W2962837550 hasRelatedWork W2964478506 @default.
- W2962837550 hasRelatedWork W2980270080 @default.
- W2962837550 hasRelatedWork W3025768905 @default.
- W2962837550 hasRelatedWork W3033834693 @default.
- W2962837550 hasRelatedWork W3087678055 @default.
- W2962837550 hasRelatedWork W3115764280 @default.
- W2962837550 hasRelatedWork W3145420286 @default.
- W2962837550 hasRelatedWork W3162412907 @default.
- W2962837550 hasRelatedWork W3211058818 @default.
- W2962837550 hasRelatedWork W98277612 @default.
- W2962837550 hasVolume "1" @default.
- W2962837550 isParatext "false" @default.
- W2962837550 isRetracted "false" @default.
- W2962837550 magId "2962837550" @default.
- W2962837550 workType "article" @default.