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- W2962839800 abstract "Graph theory provides a powerful framework to investigate brain functional connectivity networks and their modular organization. However, most graph-based methods suffer from a fundamental resolution limit that may have affected previous studies and prevented detection of modules, or communities, that are smaller than a specific scale. Surprise, a resolution-limit-free function rooted in discrete probability theory, has been recently introduced and applied to brain networks, revealing a wide size-distribution of functional modules, in contrast with many previous reports. However, the use of Surprise is limited to binary networks, while brain networks are intrinsically weighted, reflecting a continuous distribution of connectivity strengths between different brain regions. Here, we propose Asymptotical Surprise, a continuous version of Surprise, for the study of weighted brain connectivity networks, and validate this approach in synthetic networks endowed with a ground-truth modular structure. We compare Asymptotical Surprise with leading community detection methods currently in use and show its superior sensitivity in the detection of small modules even in the presence of noise and intersubject variability such as those observed in fMRI data. Finally, we apply our novel approach to functional connectivity networks from resting state fMRI experimenta, and demonstrate a heterogeneous modular organization, with a wide distribution of clusters spanning multiple scales." @default.
- W2962839800 created "2019-07-30" @default.
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- W2962839800 date "2016-09-14" @default.
- W2962839800 modified "2023-09-27" @default.
- W2962839800 title "Community detection in weighted brain connectivity networks beyond the resolution limit" @default.
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