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- W2963098387 abstract "A simple and efficient approach to enantioenriched α,β-disubstituted γ-butyrolactones has been developed through multifunctional modular organocatalysis in a highly enantioselective (>99% ee) and diastereoselective (>30:1) manner following a one-pot sequential Michael–hemiacetalization–oxidation reaction. The catalytic process has great substrate compatibility, and the products have been transformed to synthetically useful molecules. The methodology has also been applied to the formal synthesis of (+)-Pilocarpine." @default.
- W2963098387 created "2019-07-30" @default.
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- W2963098387 date "2019-07-19" @default.
- W2963098387 modified "2023-10-16" @default.
- W2963098387 title "Asymmetric Multifunctional Modular Organocatalysis: One-Pot Direct Strategy to Enantiopure α,β-Disubstituted γ-Butyrolactones" @default.
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- W2963098387 doi "https://doi.org/10.1021/acs.orglett.9b02094" @default.
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