Matches in SemOpenAlex for { <https://semopenalex.org/work/W2963474158> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2963474158 abstract "Abstract In this paper, we present a methodology to assist the offline description and online maintenance of the design space of a pharmaceutical product. The methodology is intended as a proactive risk-management tool to be included in a design space submission. First, classical feasibility analysis is exploited to obtain an offline model-based description of the design space (e.g., at the process development stage). Then, a dynamic state estimator is used to continuously adapt the model during plant operation, using measurements available from plant sensors. Surrogate-based feasibility analysis is used to continuously update the model-based description of the design space based on the up-to-date model returned by the state estimator. The tracking effectiveness of the methodology is shown for a co-milling process of a pharmaceutical production." @default.
- W2963474158 created "2019-07-30" @default.
- W2963474158 creator A5013821049 @default.
- W2963474158 creator A5057357502 @default.
- W2963474158 creator A5069724844 @default.
- W2963474158 creator A5089064192 @default.
- W2963474158 creator A5090048159 @default.
- W2963474158 date "2019-01-01" @default.
- W2963474158 modified "2023-09-23" @default.
- W2963474158 title "Real-time design space description in pharmaceutical manufacturing" @default.
- W2963474158 cites W1969871621 @default.
- W2963474158 cites W1982828755 @default.
- W2963474158 cites W2060158919 @default.
- W2963474158 cites W2086154585 @default.
- W2963474158 cites W2591062258 @default.
- W2963474158 cites W2800202855 @default.
- W2963474158 cites W2986400592 @default.
- W2963474158 doi "https://doi.org/10.1016/b978-0-12-818634-3.50111-9" @default.
- W2963474158 hasPublicationYear "2019" @default.
- W2963474158 type Work @default.
- W2963474158 sameAs 2963474158 @default.
- W2963474158 citedByCount "0" @default.
- W2963474158 crossrefType "book-chapter" @default.
- W2963474158 hasAuthorship W2963474158A5013821049 @default.
- W2963474158 hasAuthorship W2963474158A5057357502 @default.
- W2963474158 hasAuthorship W2963474158A5069724844 @default.
- W2963474158 hasAuthorship W2963474158A5089064192 @default.
- W2963474158 hasAuthorship W2963474158A5090048159 @default.
- W2963474158 hasConcept C105795698 @default.
- W2963474158 hasConcept C111919701 @default.
- W2963474158 hasConcept C127413603 @default.
- W2963474158 hasConcept C13736549 @default.
- W2963474158 hasConcept C200601418 @default.
- W2963474158 hasConcept C201995342 @default.
- W2963474158 hasConcept C204320433 @default.
- W2963474158 hasConcept C21547014 @default.
- W2963474158 hasConcept C2776207758 @default.
- W2963474158 hasConcept C2778572836 @default.
- W2963474158 hasConcept C2778938233 @default.
- W2963474158 hasConcept C33923547 @default.
- W2963474158 hasConcept C41008148 @default.
- W2963474158 hasConcept C60644358 @default.
- W2963474158 hasConcept C72434380 @default.
- W2963474158 hasConcept C86803240 @default.
- W2963474158 hasConcept C98045186 @default.
- W2963474158 hasConceptScore W2963474158C105795698 @default.
- W2963474158 hasConceptScore W2963474158C111919701 @default.
- W2963474158 hasConceptScore W2963474158C127413603 @default.
- W2963474158 hasConceptScore W2963474158C13736549 @default.
- W2963474158 hasConceptScore W2963474158C200601418 @default.
- W2963474158 hasConceptScore W2963474158C201995342 @default.
- W2963474158 hasConceptScore W2963474158C204320433 @default.
- W2963474158 hasConceptScore W2963474158C21547014 @default.
- W2963474158 hasConceptScore W2963474158C2776207758 @default.
- W2963474158 hasConceptScore W2963474158C2778572836 @default.
- W2963474158 hasConceptScore W2963474158C2778938233 @default.
- W2963474158 hasConceptScore W2963474158C33923547 @default.
- W2963474158 hasConceptScore W2963474158C41008148 @default.
- W2963474158 hasConceptScore W2963474158C60644358 @default.
- W2963474158 hasConceptScore W2963474158C72434380 @default.
- W2963474158 hasConceptScore W2963474158C86803240 @default.
- W2963474158 hasConceptScore W2963474158C98045186 @default.
- W2963474158 hasLocation W29634741581 @default.
- W2963474158 hasOpenAccess W2963474158 @default.
- W2963474158 hasPrimaryLocation W29634741581 @default.
- W2963474158 hasRelatedWork W104714782 @default.
- W2963474158 hasRelatedWork W1187316251 @default.
- W2963474158 hasRelatedWork W1971439503 @default.
- W2963474158 hasRelatedWork W2322932458 @default.
- W2963474158 hasRelatedWork W2358051984 @default.
- W2963474158 hasRelatedWork W2364542243 @default.
- W2963474158 hasRelatedWork W2378727336 @default.
- W2963474158 hasRelatedWork W2390153962 @default.
- W2963474158 hasRelatedWork W3200581808 @default.
- W2963474158 hasRelatedWork W4249055589 @default.
- W2963474158 isParatext "false" @default.
- W2963474158 isRetracted "false" @default.
- W2963474158 magId "2963474158" @default.
- W2963474158 workType "book-chapter" @default.