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- W2964010563 abstract "Hypotension, defined as a mean arterial pressure of maximum 70 mmHg, is associated with significant morbidity and mortality. The objective of this study was to determine in initially non-critical hypotensive adult patients the proportion of sepsis and if septic patients had different outcome and clinical factors than non-septic patients. This retrospective observational study was conducted over a year on adult hypotensive emergency department patients initially considered by triage as non-critical. Patients were separated into three groups: hypotensive septic patients (HSP), hypotensive non-septic infected patients (HNSIP), and other hypotensive patients (OHP). Clinical scores, signs, length of stay (LOS), and mortality were compared using analysis of variance for continuous variables and chi-square analysis for categorical variables. There were 136 (35.5%) septic patients, 37 (9.7%) with non-septic infection, and 210 (54.8%) with another cause of hypotension. Overall in-hospital mortality was 12.0% and total mortality was greater in HSP than in HNSIP (20.6% vs. 5.4%, p = 0.031) or OHP (20.6 vs. 7.6%, p < 0.001). LOS was greater for HSP when compared to HNSIP (median(IQR): 9(6–17) vs. 6(1−13), p = 0.004) and OHP (median(IQR): 9(6–17) vs. 3(1–8) days, p < 0.0001). Sepsis in a priori non-critical hypotensive adult patients, when compared with other causes of hypotension, is associated with significantly higher mortality and increased LOS. Patients that present to the emergency department and have a MAP of 70mmHg or less must be rigorously evaluated and have consistent follow-up." @default.
- W2964010563 created "2019-07-30" @default.
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- W2964010563 date "2019-12-01" @default.
- W2964010563 modified "2023-09-27" @default.
- W2964010563 title "Sepsis is frequent in initially non-critical hypotensive emergency department patients and is associated with increased mortality" @default.
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- W2964010563 doi "https://doi.org/10.1016/j.ajem.2019.158360" @default.
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