Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964088049> ?p ?o ?g. }
- W2964088049 endingPage "960" @default.
- W2964088049 startingPage "954" @default.
- W2964088049 abstract "Summary Background Autologous hematopoietic stem cell transplantation (HSCT) carries risks of infectious morbidity. We analysed epidemiology and management burden associated with invasive fungal diseases (IFDs) in children and adolescents undergoing autologous HSCT. Methods In a retrospective, single‐centre observational study, epidemiology and management burden associated with IFDs were analysed in all paediatric cancer patients who underwent autologous HSCT between 2005 and 2014. Clinical, radiographic and microbiological data were assessed up to 100 days post‐transplant. The primary endpoint was the incidence of proven, probable and possible IFDs. Further endpoints included the use of systemic antifungal agents for prevention and management of IFDs; infectious and non‐infectious comorbidities; and survival until day + 100. Results Of 95 patients (median age: 8 years; r, 0.75‐20) underwent 103 HSCT procedures for solid tumours (92) or lymphoma (11). Primary antifungal prophylaxis was administered in 49 procedures (47.5%). No single case of proven/probable IFD was diagnosed. Nine cases (8.7%) fulfilled criteria of possible pulmonary mould infection and received treatment for a median of 14 days (r, 7‐35). In an additional 12 procedures, empiric antifungal therapy with mould active agents was given for a median of 8 days (r, 3‐105). Microbiologically documented non‐fungal infections were observed in 17 procedures, and five patients were transferred to the ICU. There was one death from biopsy documented toxic endothelial damage at day 83 post‐transplant. Conclusions Autologous HSCT for solid tumours or lymphoma was associated with low morbidity from IFDs. However, utilisation of systemic antifungal agents for prevention and management of suspected IFDs was considerable." @default.
- W2964088049 created "2019-07-30" @default.
- W2964088049 creator A5009444901 @default.
- W2964088049 creator A5015760028 @default.
- W2964088049 creator A5032935188 @default.
- W2964088049 creator A5033778704 @default.
- W2964088049 creator A5051824759 @default.
- W2964088049 creator A5060726302 @default.
- W2964088049 creator A5065730219 @default.
- W2964088049 creator A5087280182 @default.
- W2964088049 date "2019-08-18" @default.
- W2964088049 modified "2023-10-16" @default.
- W2964088049 title "Epidemiology and management burden of invasive fungal infections after autologous hematopoietic stem cell transplantation: 10‐year experience at a European Pediatric Cancer Center" @default.
- W2964088049 cites W1509430389 @default.
- W2964088049 cites W1755350398 @default.
- W2964088049 cites W1949084021 @default.
- W2964088049 cites W1966639599 @default.
- W2964088049 cites W2000142787 @default.
- W2964088049 cites W2024392907 @default.
- W2964088049 cites W2042936828 @default.
- W2964088049 cites W2079606986 @default.
- W2964088049 cites W2095580652 @default.
- W2964088049 cites W2109148349 @default.
- W2964088049 cites W2109814431 @default.
- W2964088049 cites W2116440163 @default.
- W2964088049 cites W2123484965 @default.
- W2964088049 cites W2164372162 @default.
- W2964088049 cites W2166734004 @default.
- W2964088049 cites W2169721813 @default.
- W2964088049 cites W2170388896 @default.
- W2964088049 cites W2171391350 @default.
- W2964088049 cites W2268785069 @default.
- W2964088049 cites W2296751634 @default.
- W2964088049 cites W2326316924 @default.
- W2964088049 cites W2518817174 @default.
- W2964088049 cites W2592061165 @default.
- W2964088049 cites W2606658848 @default.
- W2964088049 cites W2610889635 @default.
- W2964088049 cites W2617395654 @default.
- W2964088049 cites W2799888899 @default.
- W2964088049 cites W2883043285 @default.
- W2964088049 cites W2891557623 @default.
- W2964088049 cites W2952487891 @default.
- W2964088049 doi "https://doi.org/10.1111/myc.12968" @default.
- W2964088049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31332851" @default.
- W2964088049 hasPublicationYear "2019" @default.
- W2964088049 type Work @default.
- W2964088049 sameAs 2964088049 @default.
- W2964088049 citedByCount "9" @default.
- W2964088049 countsByYear W29640880492020 @default.
- W2964088049 countsByYear W29640880492021 @default.
- W2964088049 countsByYear W29640880492022 @default.
- W2964088049 crossrefType "journal-article" @default.
- W2964088049 hasAuthorship W2964088049A5009444901 @default.
- W2964088049 hasAuthorship W2964088049A5015760028 @default.
- W2964088049 hasAuthorship W2964088049A5032935188 @default.
- W2964088049 hasAuthorship W2964088049A5033778704 @default.
- W2964088049 hasAuthorship W2964088049A5051824759 @default.
- W2964088049 hasAuthorship W2964088049A5060726302 @default.
- W2964088049 hasAuthorship W2964088049A5065730219 @default.
- W2964088049 hasAuthorship W2964088049A5087280182 @default.
- W2964088049 hasBestOaLocation W29640880491 @default.
- W2964088049 hasConcept C107130276 @default.
- W2964088049 hasConcept C120665830 @default.
- W2964088049 hasConcept C121332964 @default.
- W2964088049 hasConcept C121608353 @default.
- W2964088049 hasConcept C126322002 @default.
- W2964088049 hasConcept C141071460 @default.
- W2964088049 hasConcept C142724271 @default.
- W2964088049 hasConcept C177713679 @default.
- W2964088049 hasConcept C203092338 @default.
- W2964088049 hasConcept C204787440 @default.
- W2964088049 hasConcept C2777408962 @default.
- W2964088049 hasConcept C2779181126 @default.
- W2964088049 hasConcept C2779338263 @default.
- W2964088049 hasConcept C2780073493 @default.
- W2964088049 hasConcept C2911091166 @default.
- W2964088049 hasConcept C535046627 @default.
- W2964088049 hasConcept C61511704 @default.
- W2964088049 hasConcept C71924100 @default.
- W2964088049 hasConceptScore W2964088049C107130276 @default.
- W2964088049 hasConceptScore W2964088049C120665830 @default.
- W2964088049 hasConceptScore W2964088049C121332964 @default.
- W2964088049 hasConceptScore W2964088049C121608353 @default.
- W2964088049 hasConceptScore W2964088049C126322002 @default.
- W2964088049 hasConceptScore W2964088049C141071460 @default.
- W2964088049 hasConceptScore W2964088049C142724271 @default.
- W2964088049 hasConceptScore W2964088049C177713679 @default.
- W2964088049 hasConceptScore W2964088049C203092338 @default.
- W2964088049 hasConceptScore W2964088049C204787440 @default.
- W2964088049 hasConceptScore W2964088049C2777408962 @default.
- W2964088049 hasConceptScore W2964088049C2779181126 @default.
- W2964088049 hasConceptScore W2964088049C2779338263 @default.
- W2964088049 hasConceptScore W2964088049C2780073493 @default.
- W2964088049 hasConceptScore W2964088049C2911091166 @default.
- W2964088049 hasConceptScore W2964088049C535046627 @default.
- W2964088049 hasConceptScore W2964088049C61511704 @default.
- W2964088049 hasConceptScore W2964088049C71924100 @default.