FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964235581> ?p ?o ?g. }

• W2964235581 endingPage "144" @default.
• W2964235581 startingPage "138" @default.
• W2964235581 abstract "Objectives Whether epidermal growth factor receptor tyrosine-kinase inhibitors (EGFR-TKIs) plus local consolidative therapy (LCT) has survival benefit over EGFR-TKIs alone in lung adenocarcinoma patients with EGFR mutation and bone oligometastases remains controversial. Materials and methods We conducted a retrospective study to assess the effects of LCT in lung adenocarcinoma patients with bone oligometastases and EGFR mutation. The primary endpoint was overall survival (OS); the secondary endpoints was progression-free survival (PFS). Results A total of 127 lung adenocarcinoma patients with EGFR mutation and bone oligometastases were assessed, including 65 patients received EGFR-TKIs alone (monotherapy group) and 62 patients received EGFR-TKIs plus local consolidative therapy (LCT) (combination group). Addition of LCT was associated with significantly longer OS (36.3 vs. 21.0 months, P = 0.01; hazard ratio [HR] = 0.537, 95% confidence interval [CI]: 0.360-0.801, p = 0.01) and PFS (14.0 vs. 8.1 months, P = 0.01; HR = 0.613, 95%CI: 0.427-0.879, p = 0.01) in the whole cohort. Conclusion In lung adenocarcinoma patients with EGFR-mutation and bone oligometastases, LCT plus EGFR-TKIs therapy is associated with significantly longer OS and PFS compared with EGFR-TKIs therapy alone, indicating that LCT plus EGFR-TKIs therapy might be a better therapeutic option for this patient population." @default.
• W2964235581 created "2019-07-30" @default.
• W2964235581 creator A5009268385 @default.
• W2964235581 creator A5024307244 @default.
• W2964235581 creator A5028624269 @default.
• W2964235581 creator A5033444810 @default.
• W2964235581 creator A5036188864 @default.
• W2964235581 creator A5047962353 @default.
• W2964235581 creator A5058563343 @default.
• W2964235581 creator A5064221485 @default.
• W2964235581 creator A5073842773 @default.
• W2964235581 creator A5078137559 @default.
• W2964235581 date "2019-09-01" @default.
• W2964235581 modified "2023-10-16" @default.
• W2964235581 title "Additional local consolidative therapy has survival benefit over EGFR tyrosine kinase inhibitors alone in bone oligometastatic lung adenocarcinoma patients" @default.
• W2964235581 cites W1983919424 @default.
• W2964235581 cites W2012295597 @default.
• W2964235581 cites W2027242209 @default.
• W2964235581 cites W2052354574 @default.
• W2964235581 cites W2080765629 @default.
• W2964235581 cites W2108168221 @default.
• W2964235581 cites W2135192471 @default.
• W2964235581 cites W2136601558 @default.
• W2964235581 cites W2150371178 @default.
• W2964235581 cites W2151204647 @default.
• W2964235581 cites W2153694235 @default.
• W2964235581 cites W2155338842 @default.
• W2964235581 cites W2176128299 @default.
• W2964235581 cites W2192135274 @default.
• W2964235581 cites W2319874020 @default.
• W2964235581 cites W2536331410 @default.
• W2964235581 cites W2536769127 @default.
• W2964235581 cites W2560717039 @default.
• W2964235581 cites W2561956624 @default.
• W2964235581 cites W2619919786 @default.
• W2964235581 cites W2761351587 @default.
• W2964235581 cites W2893690704 @default.
• W2964235581 cites W2913736283 @default.
• W2964235581 cites W4240340450 @default.
• W2964235581 doi "https://doi.org/10.1016/j.lungcan.2019.07.024" @default.
• W2964235581 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31446986" @default.
• W2964235581 hasPublicationYear "2019" @default.
• W2964235581 type Work @default.
• W2964235581 sameAs 2964235581 @default.
• W2964235581 citedByCount "12" @default.
• W2964235581 countsByYear W29642355812020 @default.
• W2964235581 countsByYear W29642355812021 @default.
• W2964235581 countsByYear W29642355812022 @default.
• W2964235581 countsByYear W29642355812023 @default.
• W2964235581 crossrefType "journal-article" @default.
• W2964235581 hasAuthorship W2964235581A5009268385 @default.
• W2964235581 hasAuthorship W2964235581A5024307244 @default.
• W2964235581 hasAuthorship W2964235581A5028624269 @default.
• W2964235581 hasAuthorship W2964235581A5033444810 @default.
• W2964235581 hasAuthorship W2964235581A5036188864 @default.
• W2964235581 hasAuthorship W2964235581A5047962353 @default.
• W2964235581 hasAuthorship W2964235581A5058563343 @default.
• W2964235581 hasAuthorship W2964235581A5064221485 @default.
• W2964235581 hasAuthorship W2964235581A5073842773 @default.
• W2964235581 hasAuthorship W2964235581A5078137559 @default.
• W2964235581 hasConcept C121608353 @default.
• W2964235581 hasConcept C126322002 @default.
• W2964235581 hasConcept C143998085 @default.
• W2964235581 hasConcept C168563851 @default.
• W2964235581 hasConcept C203092338 @default.
• W2964235581 hasConcept C207103383 @default.
• W2964235581 hasConcept C2776256026 @default.
• W2964235581 hasConcept C2779438470 @default.
• W2964235581 hasConcept C2780580887 @default.
• W2964235581 hasConcept C2781182431 @default.
• W2964235581 hasConcept C2781230642 @default.
• W2964235581 hasConcept C2908647359 @default.
• W2964235581 hasConcept C44249647 @default.
• W2964235581 hasConcept C71924100 @default.
• W2964235581 hasConcept C99454951 @default.
• W2964235581 hasConceptScore W2964235581C121608353 @default.
• W2964235581 hasConceptScore W2964235581C126322002 @default.
• W2964235581 hasConceptScore W2964235581C143998085 @default.
• W2964235581 hasConceptScore W2964235581C168563851 @default.
• W2964235581 hasConceptScore W2964235581C203092338 @default.
• W2964235581 hasConceptScore W2964235581C207103383 @default.
• W2964235581 hasConceptScore W2964235581C2776256026 @default.
• W2964235581 hasConceptScore W2964235581C2779438470 @default.
• W2964235581 hasConceptScore W2964235581C2780580887 @default.
• W2964235581 hasConceptScore W2964235581C2781182431 @default.
• W2964235581 hasConceptScore W2964235581C2781230642 @default.
• W2964235581 hasConceptScore W2964235581C2908647359 @default.
• W2964235581 hasConceptScore W2964235581C44249647 @default.
• W2964235581 hasConceptScore W2964235581C71924100 @default.
• W2964235581 hasConceptScore W2964235581C99454951 @default.
• W2964235581 hasLocation W29642355811 @default.
• W2964235581 hasLocation W29642355812 @default.
• W2964235581 hasOpenAccess W2964235581 @default.
• W2964235581 hasPrimaryLocation W29642355811 @default.
• W2964235581 hasRelatedWork W1966428098 @default.
• W2964235581 hasRelatedWork W1973817016 @default.
• W2964235581 hasRelatedWork W2014496389 @default.
• W2964235581 hasRelatedWork W2024244267 @default.

• next