Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964247626> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2964247626 abstract "Context: Screening of natural biomolecules from microalgae. Background: The microalgae were recognized for their biological and pharmacological importance of active natural products with high antioxidant and antiproliferative profile. In the preliminary screening, three species Nannochloropsis sp. (NC) (green algae), Amphora sp. (diatom), and Nostoc sp. (blue-green algae) were tested and Nannochloropsis was selected based on their scavenging properties. Objective: The objective of the study is to explore the biological information of microalgal species where the clinical investigation is still quite limited. Materials and Methods: The phytochemical screening of selected NC. primarily comprises saponins, terpenoids, flavonoids, and phenols which were confirmed by high-performance thin-layer chromatography, Fourier transform infrared, and gas chromatography–mass spectra analysis. Results: The ethyl acetate extract Nannochloropsis hexane (EAENH) fraction showed 40.61 mg GAE/g, 68.77 mg QE/g, 5.73 mg/g, and 57.38 mg CHL/g for total phenolic, flavonoid, carotenoid, and sterol content, respectively. Moreover, antioxidant activities were evaluated for the extract showing high flavonoid and phenolic contents after partial purification with hexane. The half inhibitory concentration (IC50) values for EAENH was found to be 13.9, 21.22, and 14.58 μg/mL for 1,1-diphenyl-2-picrylhydrazyl radical, hydrogen peroxide, and reducing power assays, respectively. The antiproliferative activity of EAENH on human non-small lung cancer cell line (A549) IC50 value was 175 μg/mL using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Conclusion: The present study confirmed that the bioactive components present in the EAENH were accountable for excellent antioxidant and cytotoxic properties." @default.
- W2964247626 created "2019-07-30" @default.
- W2964247626 creator A5009491416 @default.
- W2964247626 creator A5013397460 @default.
- W2964247626 creator A5036533491 @default.
- W2964247626 creator A5064750912 @default.
- W2964247626 date "2019-01-01" @default.
- W2964247626 modified "2023-10-18" @default.
- W2964247626 title "Chemical composition, antioxidant, and cytotoxic potential of Nannochloropsis species extracts" @default.
- W2964247626 doi "https://doi.org/10.4103/jnsbm.jnsbm_208_18" @default.
- W2964247626 hasPublicationYear "2019" @default.
- W2964247626 type Work @default.
- W2964247626 sameAs 2964247626 @default.
- W2964247626 citedByCount "3" @default.
- W2964247626 countsByYear W29642476262020 @default.
- W2964247626 countsByYear W29642476262021 @default.
- W2964247626 crossrefType "journal-article" @default.
- W2964247626 hasAuthorship W2964247626A5009491416 @default.
- W2964247626 hasAuthorship W2964247626A5013397460 @default.
- W2964247626 hasAuthorship W2964247626A5036533491 @default.
- W2964247626 hasAuthorship W2964247626A5064750912 @default.
- W2964247626 hasConcept C151730666 @default.
- W2964247626 hasConcept C185592680 @default.
- W2964247626 hasConcept C195475562 @default.
- W2964247626 hasConcept C202751555 @default.
- W2964247626 hasConcept C206103511 @default.
- W2964247626 hasConcept C2777752497 @default.
- W2964247626 hasConcept C2778004101 @default.
- W2964247626 hasConcept C2779054382 @default.
- W2964247626 hasConcept C2779343474 @default.
- W2964247626 hasConcept C2779858419 @default.
- W2964247626 hasConcept C2781401929 @default.
- W2964247626 hasConcept C31903555 @default.
- W2964247626 hasConcept C43617362 @default.
- W2964247626 hasConcept C55493867 @default.
- W2964247626 hasConcept C70899900 @default.
- W2964247626 hasConcept C86803240 @default.
- W2964247626 hasConceptScore W2964247626C151730666 @default.
- W2964247626 hasConceptScore W2964247626C185592680 @default.
- W2964247626 hasConceptScore W2964247626C195475562 @default.
- W2964247626 hasConceptScore W2964247626C202751555 @default.
- W2964247626 hasConceptScore W2964247626C206103511 @default.
- W2964247626 hasConceptScore W2964247626C2777752497 @default.
- W2964247626 hasConceptScore W2964247626C2778004101 @default.
- W2964247626 hasConceptScore W2964247626C2779054382 @default.
- W2964247626 hasConceptScore W2964247626C2779343474 @default.
- W2964247626 hasConceptScore W2964247626C2779858419 @default.
- W2964247626 hasConceptScore W2964247626C2781401929 @default.
- W2964247626 hasConceptScore W2964247626C31903555 @default.
- W2964247626 hasConceptScore W2964247626C43617362 @default.
- W2964247626 hasConceptScore W2964247626C55493867 @default.
- W2964247626 hasConceptScore W2964247626C70899900 @default.
- W2964247626 hasConceptScore W2964247626C86803240 @default.
- W2964247626 hasLocation W29642476261 @default.
- W2964247626 hasOpenAccess W2964247626 @default.
- W2964247626 hasPrimaryLocation W29642476261 @default.
- W2964247626 hasRelatedWork W2183663817 @default.
- W2964247626 hasRelatedWork W2188115499 @default.
- W2964247626 hasRelatedWork W2378086718 @default.
- W2964247626 hasRelatedWork W2586736920 @default.
- W2964247626 hasRelatedWork W2912346484 @default.
- W2964247626 hasRelatedWork W2944661893 @default.
- W2964247626 hasRelatedWork W3113762632 @default.
- W2964247626 hasRelatedWork W3120957829 @default.
- W2964247626 hasRelatedWork W4281645458 @default.
- W2964247626 hasRelatedWork W2547070443 @default.
- W2964247626 isParatext "false" @default.
- W2964247626 isRetracted "false" @default.
- W2964247626 magId "2964247626" @default.
- W2964247626 workType "article" @default.