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• W2964308084 abstract "Vascular cognitive impairment (VCI) is a clinical syndrome that encompasses all forms of cognitive deficits caused by cerebrovascular disease, from mild cognitive impairment (MCI) to dementia. Vascular dementia (VD),the second most common type of dementia after Alzheimer's disease (AD), accounts for approximately 20% of dementia patients.Ferroptosis is a recently defined iron-dependent form of cell death, which is distinct from apoptosis, necrosis, autophagy and other forms of cell death. Emerging evidence suggested that ferroptosis has significant implications in neurological diseases such as stroke, traumatic brain injury and AD.And ferroptosis inhibition have obvious neuroprotective effect and ameliorate cognitive impairment in various animals models . Here,we summarizes the underlying mechanisms of ferroptosis, and reviews the close relationship between ferroptosis and VCI." @default.
• W2964308084 created "2019-07-30" @default.
• W2964308084 creator A5038350185 @default.
• W2964308084 creator A5090906354 @default.
• W2964308084 date "2019-08-06" @default.
• W2964308084 modified "2023-10-11" @default.
• W2964308084 title "The Emerging Roles of Ferroptosis in Vascular Cognitive Impairment" @default.
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