FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964369512> ?p ?o ?g. }

• W2964369512 abstract "To date, no studies have investigated the expression of Doublecortin (DCX) in pituitary adenomas or evaluated the clinical value of DCX in the diagnosis of pituitary adenomas. This study aims to determine the expression levels of DCX in pituitary adenomas and to investigate its role in the staging of this condition.Forty-six patients with pituitary adenomas were recruited. The expression of DCX in tumor sections from pituitary adenomas was determined using immunohistochemistry and quantitative real-time polymerase chain reaction. Tumors were classified as either invasive or non-invasive on the basis of clinical stage and using the Knosp grading system. Differences in the expression of DCX and its association with clinical characteristics were investigated. The potential of the measurement of DCX levels for distinguishing between invasive and non-invasive tumors was estimated using receiver operating characteristic (ROC) analysis.Expression of DCX were correlated with Knosp grade. No significant association was observed between DCX level and the clinical stage of the tumors. The expression of DCX was higher in tumors with Knosp 3 and lowest in Knosp 1, at both the mRNA and protein levels. Using DCX as a biomarker for the prediction of tumor invasiveness in pituitary adenoma patients, the area under the ROC curve was 0.829 (95% confidence interval, 0.6-28.1), which is higher than that obtained using Knosp grade.The expression of DCX is related to the Knosp grade of pituitary adenoma. DCX levels can be used as a biomarker for tumor invasiveness prediction in pituitary adenoma patients." @default.
• W2964369512 created "2019-08-13" @default.
• W2964369512 creator A5022773608 @default.
• W2964369512 creator A5034711230 @default.
• W2964369512 creator A5037873650 @default.
• W2964369512 creator A5040796850 @default.
• W2964369512 creator A5061308332 @default.
• W2964369512 creator A5062431042 @default.
• W2964369512 creator A5063022663 @default.
• W2964369512 date "2019-12-01" @default.
• W2964369512 modified "2023-09-26" @default.
• W2964369512 title "Expression and clinical significance of doublecortin (DCX) in pituitary adenoma" @default.
• W2964369512 cites W1485539251 @default.
• W2964369512 cites W1493959924 @default.
• W2964369512 cites W1530507664 @default.
• W2964369512 cites W1824650450 @default.
• W2964369512 cites W2001117361 @default.
• W2964369512 cites W2003290522 @default.
• W2964369512 cites W2024490679 @default.
• W2964369512 cites W2032924639 @default.
• W2964369512 cites W2064697437 @default.
• W2964369512 cites W2068294480 @default.
• W2964369512 cites W2089394861 @default.
• W2964369512 cites W2100301546 @default.
• W2964369512 cites W2102000647 @default.
• W2964369512 cites W2120111938 @default.
• W2964369512 cites W2131554707 @default.
• W2964369512 cites W2135860557 @default.
• W2964369512 cites W2146162030 @default.
• W2964369512 cites W2150163498 @default.
• W2964369512 cites W2156198928 @default.
• W2964369512 cites W2165097825 @default.
• W2964369512 cites W2561821804 @default.
• W2964369512 cites W2582160238 @default.
• W2964369512 cites W2750666238 @default.
• W2964369512 cites W2754676964 @default.
• W2964369512 cites W2756117009 @default.
• W2964369512 doi "https://doi.org/10.1016/j.bulcan.2019.05.009" @default.
• W2964369512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31376915" @default.
• W2964369512 hasPublicationYear "2019" @default.
• W2964369512 type Work @default.
• W2964369512 sameAs 2964369512 @default.
• W2964369512 citedByCount "2" @default.
• W2964369512 countsByYear W29643695122021 @default.
• W2964369512 countsByYear W29643695122023 @default.
• W2964369512 crossrefType "journal-article" @default.
• W2964369512 hasAuthorship W2964369512A5022773608 @default.
• W2964369512 hasAuthorship W2964369512A5034711230 @default.
• W2964369512 hasAuthorship W2964369512A5037873650 @default.
• W2964369512 hasAuthorship W2964369512A5040796850 @default.
• W2964369512 hasAuthorship W2964369512A5061308332 @default.
• W2964369512 hasAuthorship W2964369512A5062431042 @default.
• W2964369512 hasAuthorship W2964369512A5063022663 @default.
• W2964369512 hasConcept C126322002 @default.
• W2964369512 hasConcept C142724271 @default.
• W2964369512 hasConcept C143998085 @default.
• W2964369512 hasConcept C148762608 @default.
• W2964369512 hasConcept C18903297 @default.
• W2964369512 hasConcept C204232928 @default.
• W2964369512 hasConcept C2776464000 @default.
• W2964369512 hasConcept C2777286243 @default.
• W2964369512 hasConcept C2777428134 @default.
• W2964369512 hasConcept C2777658017 @default.
• W2964369512 hasConcept C2779318953 @default.
• W2964369512 hasConcept C2781461022 @default.
• W2964369512 hasConcept C2908910360 @default.
• W2964369512 hasConcept C71315377 @default.
• W2964369512 hasConcept C71924100 @default.
• W2964369512 hasConcept C86803240 @default.
• W2964369512 hasConceptScore W2964369512C126322002 @default.
• W2964369512 hasConceptScore W2964369512C142724271 @default.
• W2964369512 hasConceptScore W2964369512C143998085 @default.
• W2964369512 hasConceptScore W2964369512C148762608 @default.
• W2964369512 hasConceptScore W2964369512C18903297 @default.
• W2964369512 hasConceptScore W2964369512C204232928 @default.
• W2964369512 hasConceptScore W2964369512C2776464000 @default.
• W2964369512 hasConceptScore W2964369512C2777286243 @default.
• W2964369512 hasConceptScore W2964369512C2777428134 @default.
• W2964369512 hasConceptScore W2964369512C2777658017 @default.
• W2964369512 hasConceptScore W2964369512C2779318953 @default.
• W2964369512 hasConceptScore W2964369512C2781461022 @default.
• W2964369512 hasConceptScore W2964369512C2908910360 @default.
• W2964369512 hasConceptScore W2964369512C71315377 @default.
• W2964369512 hasConceptScore W2964369512C71924100 @default.
• W2964369512 hasConceptScore W2964369512C86803240 @default.
• W2964369512 hasLocation W29643695121 @default.
• W2964369512 hasLocation W29643695122 @default.
• W2964369512 hasOpenAccess W2964369512 @default.
• W2964369512 hasPrimaryLocation W29643695121 @default.
• W2964369512 hasRelatedWork W1489359833 @default.
• W2964369512 hasRelatedWork W201409066 @default.
• W2964369512 hasRelatedWork W2088496903 @default.
• W2964369512 hasRelatedWork W2141835612 @default.
• W2964369512 hasRelatedWork W2144441522 @default.
• W2964369512 hasRelatedWork W2350134505 @default.
• W2964369512 hasRelatedWork W2351265804 @default.
• W2964369512 hasRelatedWork W2354238097 @default.
• W2964369512 hasRelatedWork W2366082711 @default.
• W2964369512 hasRelatedWork W2606153363 @default.
• W2964369512 isParatext "false" @default.

• next