FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964507444> ?p ?o ?g. }

• W2964507444 endingPage "2569" @default.
• W2964507444 startingPage "2563" @default.
• W2964507444 abstract "Frailty is a condition of decreased physiologic reserve and increased vulnerability to stressors. Frailty in combination with inflammation has been associated with increased mortality risk in adults with advanced chronic kidney disease (CKD). This study aimed to investigate prevalence and outcomes associated with a frailty-inflammation phenotype, or “fragility,” in children with CKD. We analyzed 557 children (age 6–19 years, eGFR 30–90 ml/min/1.73 m2) from the Chronic Kidney Disease in Children (CKiD) study. Based on adult models, the CKiD fragility model included four indicators: (1) suboptimal growth/weight gain (BMI < 5th percentile-for-height-age, deceleration ≥ 10 BMI-for-height-age percentiles/1 year, height-for-age percentile < 3rd or deceleration ≥ 10 height percentiles/1 year); (2) low muscle mass (mid-upper-arm circumference < 5th percentile or deceleration ≥ 10 percentiles/1 year); (3) fatigue (parent/child report); (4) inflammation (CRP > 3 mg/l). Logistic regression was used to evaluate association of fragility indicators with three adverse outcomes: frequent infection (> 1 per year/3 years), hospitalization (any), and rapid CKD progression (decline in eGFR > 30% or initiation of renal replacement therapy within 3 years). Prevalence of fragility indicators 1 year after study entry were 39% (suboptimal growth/weight gain), 62% (low muscle mass), 29% (fatigue), and 18% (inflammation). Prevalence of adverse outcomes during the subsequent 3 years were 13% (frequent infection), 22% (hospitalization), and 17% (rapid CKD progression). Children with ≥ 3 fragility indicators had 3.16-fold odds of frequent infection and 2.81-fold odds of hospitalization, but did not have rapid CKD progression. A fragility phenotype, characterized by the presence of ≥ 3 indicators, is associated with adverse outcomes, including infection and hospitalization in children with CKD." @default.
• W2964507444 created "2019-08-13" @default.
• W2964507444 creator A5000807817 @default.
• W2964507444 creator A5010894164 @default.
• W2964507444 creator A5015166733 @default.
• W2964507444 creator A5027825347 @default.
• W2964507444 creator A5046247199 @default.
• W2964507444 creator A5056623045 @default.
• W2964507444 date "2019-08-02" @default.
• W2964507444 modified "2023-09-30" @default.
• W2964507444 title "Prevalence and outcomes of fragility: a frailty-inflammation phenotype in children with chronic kidney disease" @default.
• W2964507444 cites W1752117190 @default.
• W2964507444 cites W1940450382 @default.
• W2964507444 cites W1990210932 @default.
• W2964507444 cites W1993018087 @default.
• W2964507444 cites W2040616813 @default.
• W2964507444 cites W2045649971 @default.
• W2964507444 cites W2073120237 @default.
• W2964507444 cites W2100619505 @default.
• W2964507444 cites W2104859015 @default.
• W2964507444 cites W2138797833 @default.
• W2964507444 cites W2150951694 @default.
• W2964507444 cites W2159750202 @default.
• W2964507444 cites W2164059021 @default.
• W2964507444 cites W2164186760 @default.
• W2964507444 cites W2211694691 @default.
• W2964507444 cites W2273264565 @default.
• W2964507444 cites W2323149989 @default.
• W2964507444 cites W2475102738 @default.
• W2964507444 cites W2514207831 @default.
• W2964507444 cites W2550722383 @default.
• W2964507444 cites W2605122097 @default.
• W2964507444 cites W2766990640 @default.
• W2964507444 cites W2774428646 @default.
• W2964507444 cites W2792071818 @default.
• W2964507444 cites W2796006113 @default.
• W2964507444 cites W2800452149 @default.
• W2964507444 cites W2903139083 @default.
• W2964507444 cites W2905058333 @default.
• W2964507444 cites W2906496589 @default.
• W2964507444 cites W2914969935 @default.
• W2964507444 doi "https://doi.org/10.1007/s00467-019-04313-8" @default.
• W2964507444 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6819247" @default.
• W2964507444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31375914" @default.
• W2964507444 hasPublicationYear "2019" @default.
• W2964507444 type Work @default.
• W2964507444 sameAs 2964507444 @default.
• W2964507444 citedByCount "21" @default.
• W2964507444 countsByYear W29645074442019 @default.
• W2964507444 countsByYear W29645074442020 @default.
• W2964507444 countsByYear W29645074442021 @default.
• W2964507444 countsByYear W29645074442022 @default.
• W2964507444 countsByYear W29645074442023 @default.
• W2964507444 crossrefType "journal-article" @default.
• W2964507444 hasAuthorship W2964507444A5000807817 @default.
• W2964507444 hasAuthorship W2964507444A5010894164 @default.
• W2964507444 hasAuthorship W2964507444A5015166733 @default.
• W2964507444 hasAuthorship W2964507444A5027825347 @default.
• W2964507444 hasAuthorship W2964507444A5046247199 @default.
• W2964507444 hasAuthorship W2964507444A5056623045 @default.
• W2964507444 hasBestOaLocation W29645074442 @default.
• W2964507444 hasConcept C105795698 @default.
• W2964507444 hasConcept C122048520 @default.
• W2964507444 hasConcept C126322002 @default.
• W2964507444 hasConcept C156957248 @default.
• W2964507444 hasConcept C187212893 @default.
• W2964507444 hasConcept C2778653478 @default.
• W2964507444 hasConcept C2780221984 @default.
• W2964507444 hasConcept C33923547 @default.
• W2964507444 hasConcept C54847362 @default.
• W2964507444 hasConcept C71924100 @default.
• W2964507444 hasConceptScore W2964507444C105795698 @default.
• W2964507444 hasConceptScore W2964507444C122048520 @default.
• W2964507444 hasConceptScore W2964507444C126322002 @default.
• W2964507444 hasConceptScore W2964507444C156957248 @default.
• W2964507444 hasConceptScore W2964507444C187212893 @default.
• W2964507444 hasConceptScore W2964507444C2778653478 @default.
• W2964507444 hasConceptScore W2964507444C2780221984 @default.
• W2964507444 hasConceptScore W2964507444C33923547 @default.
• W2964507444 hasConceptScore W2964507444C54847362 @default.
• W2964507444 hasConceptScore W2964507444C71924100 @default.
• W2964507444 hasFunder F4320337338 @default.
• W2964507444 hasFunder F4320337357 @default.
• W2964507444 hasFunder F4320337611 @default.
• W2964507444 hasIssue "12" @default.
• W2964507444 hasLocation W29645074441 @default.
• W2964507444 hasLocation W29645074442 @default.
• W2964507444 hasLocation W29645074443 @default.
• W2964507444 hasOpenAccess W2964507444 @default.
• W2964507444 hasPrimaryLocation W29645074441 @default.
• W2964507444 hasRelatedWork W2001092908 @default.
• W2964507444 hasRelatedWork W2049374669 @default.
• W2964507444 hasRelatedWork W2111572540 @default.
• W2964507444 hasRelatedWork W2161578472 @default.
• W2964507444 hasRelatedWork W2319948171 @default.
• W2964507444 hasRelatedWork W2955980042 @default.
• W2964507444 hasRelatedWork W3003571257 @default.
• W2964507444 hasRelatedWork W4295296536 @default.

• next