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• W2964567605 abstract "Amniotic membrane (AM) and umbilical cord (UC) are well known to have anti-inflammatory properties and have been shown to promote healing in various orthopedic indications. This study investigated whether intra-articular injection of AM/UC particulate matrix promotes healing of partial rotator cuff tears (RCTs).A case series was performed on 10 patients that received injection of 50 mg AM/UC for partial RCTs that were refractory to conservative treatment. Outcomes included Penn Shoulder Score (PSS) questionnaire, range of motion examination, and magnetic resonance imaging (MRI) analysis before and at 6 months. Final MRI analysis was performed by a musculoskeletal radiologist in a blinded fashion.Average PSS score (out of 100) increased from 46.8 ± 23.7 at baseline to 82.0 ± 19.1 at 6 months. The average PSS sub-scores of pain, satisfaction, and function increased 78.4%, 37.1%, and 82.3% from baseline, respectively. The subject's range of motion was 77.9% at baseline and increased to 99.9% at 6-months. Follow-up MRI scans did not demonstrate any significant change in RCT size. No adverse events were noted.This small case series provides preliminary data for use of cryopreserved AM/UC particulate matrix in patients with refractory partial RCTs." @default.
• W2964567605 created "2019-08-13" @default.
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• W2964567605 date "2019-07-01" @default.
• W2964567605 modified "2023-10-06" @default.
• W2964567605 title "Cryopreserved amniotic membrane and umbilical cord particulate matrix for partial rotator cuff tears" @default.
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• W2964567605 doi "https://doi.org/10.1097/md.0000000000016569" @default.
• W2964567605 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6709267" @default.
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