FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2964617070> ?p ?o ?g. }

• W2964617070 endingPage "7550" @default.
• W2964617070 startingPage "7539" @default.
• W2964617070 abstract "The rostromedioventral striatum is critical for behavior dependent on evaluating rewards. We asked what contribution tonically active neurons (TANs), the putative striatal cholinergic interneurons, make in coding reward value in this part of the striatum. Two female monkeys were given the option to accept or reject an offered reward in each trial, the value of which was signaled by a visual cue. Forty-five percent of the TANs use temporally modulated activity to encode information about discounted value. These responses were significantly better represented using principal component analysis than by just counting spikes. The temporal coding is straightforward: the spikes are distributed according to a sinusoidal envelope of activity that changes gain, ranging from positive to negative according to discounted value. Our results show that the information about the relative value of an offered reward is temporally encoded in neural spike trains of TANs. This temporal coding may allow well tuned, coordinated behavior to emerge. <b>SIGNIFICANCE STATEMENT</b> Ever since the discovery that neurons use trains of pulses to transmit information, it seemed self-evident that information would be encoded into the pattern of the spikes. However, there is not much evidence that spike patterns encode cognitive information. We find that a set of interneurons, the tonically active neurons (TANs) in monkeys9 striatum, use temporal patterns of response to encode information about the discounted value of offered rewards. The code seems straightforward: a sinusoidal envelope that changes gain according to the discounted value of the offer, describes the rate of spiking across time. This temporal modulation may provide a means to synchronize these interneurons and the activity of other neural elements including principal output neurons." @default.
• W2964617070 created "2019-08-13" @default.
• W2964617070 creator A5024704279 @default.
• W2964617070 creator A5025642798 @default.
• W2964617070 creator A5029623610 @default.
• W2964617070 creator A5045067652 @default.
• W2964617070 creator A5062445350 @default.
• W2964617070 creator A5064289888 @default.
• W2964617070 date "2019-07-30" @default.
• W2964617070 modified "2023-10-11" @default.
• W2964617070 title "Temporal Coding of Reward Value in Monkey Ventral Striatal Tonically Active Neurons" @default.
• W2964617070 cites W1487894289 @default.
• W2964617070 cites W1518999905 @default.
• W2964617070 cites W1534301864 @default.
• W2964617070 cites W1596940277 @default.
• W2964617070 cites W1622774380 @default.
• W2964617070 cites W1900554569 @default.
• W2964617070 cites W1964309659 @default.
• W2964617070 cites W1976864358 @default.
• W2964617070 cites W1980540768 @default.
• W2964617070 cites W1985938249 @default.
• W2964617070 cites W1991832901 @default.
• W2964617070 cites W2000244885 @default.
• W2964617070 cites W2003412240 @default.
• W2964617070 cites W2004741670 @default.
• W2964617070 cites W2009324585 @default.
• W2964617070 cites W2012187737 @default.
• W2964617070 cites W2020361904 @default.
• W2964617070 cites W2020660611 @default.
• W2964617070 cites W2022764592 @default.
• W2964617070 cites W2027537563 @default.
• W2964617070 cites W2031018479 @default.
• W2964617070 cites W2033904402 @default.
• W2964617070 cites W2035069294 @default.
• W2964617070 cites W2041440158 @default.
• W2964617070 cites W2048941040 @default.
• W2964617070 cites W2052886688 @default.
• W2964617070 cites W2058658746 @default.
• W2964617070 cites W2062899906 @default.
• W2964617070 cites W2067055492 @default.
• W2964617070 cites W2070485861 @default.
• W2964617070 cites W2075994330 @default.
• W2964617070 cites W2081547332 @default.
• W2964617070 cites W2084374696 @default.
• W2964617070 cites W2088386233 @default.
• W2964617070 cites W2093642963 @default.
• W2964617070 cites W2105987091 @default.
• W2964617070 cites W2110731384 @default.
• W2964617070 cites W2110925924 @default.
• W2964617070 cites W2113894928 @default.
• W2964617070 cites W2125946589 @default.
• W2964617070 cites W2136267239 @default.
• W2964617070 cites W2148134595 @default.
• W2964617070 cites W2164908099 @default.
• W2964617070 cites W2165388543 @default.
• W2964617070 cites W2181008001 @default.
• W2964617070 cites W2199533381 @default.
• W2964617070 cites W2237465850 @default.
• W2964617070 cites W2237468501 @default.
• W2964617070 cites W2258526350 @default.
• W2964617070 cites W2259589351 @default.
• W2964617070 cites W2329323183 @default.
• W2964617070 cites W2560387223 @default.
• W2964617070 cites W2626341590 @default.
• W2964617070 cites W2738564809 @default.
• W2964617070 cites W2740027912 @default.
• W2964617070 cites W2757335035 @default.
• W2964617070 doi "https://doi.org/10.1523/jneurosci.0869-19.2019" @default.
• W2964617070 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6750938" @default.
• W2964617070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31363063" @default.
• W2964617070 hasPublicationYear "2019" @default.
• W2964617070 type Work @default.
• W2964617070 sameAs 2964617070 @default.
• W2964617070 citedByCount "8" @default.
• W2964617070 countsByYear W29646170702020 @default.
• W2964617070 countsByYear W29646170702021 @default.
• W2964617070 countsByYear W29646170702022 @default.
• W2964617070 countsByYear W29646170702023 @default.
• W2964617070 crossrefType "journal-article" @default.
• W2964617070 hasAuthorship W2964617070A5024704279 @default.
• W2964617070 hasAuthorship W2964617070A5025642798 @default.
• W2964617070 hasAuthorship W2964617070A5029623610 @default.
• W2964617070 hasAuthorship W2964617070A5045067652 @default.
• W2964617070 hasAuthorship W2964617070A5062445350 @default.
• W2964617070 hasAuthorship W2964617070A5064289888 @default.
• W2964617070 hasBestOaLocation W29646170701 @default.
• W2964617070 hasConcept C104317684 @default.
• W2964617070 hasConcept C105795698 @default.
• W2964617070 hasConcept C115903868 @default.
• W2964617070 hasConcept C15744967 @default.
• W2964617070 hasConcept C169760540 @default.
• W2964617070 hasConcept C179518139 @default.
• W2964617070 hasConcept C2776743251 @default.
• W2964617070 hasConcept C2780062018 @default.
• W2964617070 hasConcept C2781390188 @default.
• W2964617070 hasConcept C2909946758 @default.
• W2964617070 hasConcept C33923547 @default.
• W2964617070 hasConcept C41008148 @default.

• next